为患有多囊性肾病的婴儿提供支持:综合方法》。

Pub Date : 2024-10-01 DOI:10.1891/NN-2024-0007
Haley M Baker, Amy J Jnah
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引用次数: 0

摘要

多囊性发育不良肾(MCDK)是一种先天性肾脏疾病,其特点是存在大小不等的非沟通性囊肿,妨碍肾实质的发育和功能。肾功能与对侧肾脏的功能和对治疗的反应有关。单侧和孤立的病例通常无症状,疗效较好,而严重的双侧肾功能失调死亡率较高。我们介绍了一例在非三级中心诊断的左侧 MCDK 和右侧肾发育不良病例。此外,我们还回顾了 MCDK 的流行病学、表观遗传学和病理生理学。我们还简要讨论了产前、产中和产后肾功能监测方法,以帮助新生儿医疗服务提供者与儿科肾病学和泌尿学专家合作。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
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Supporting Infants with Multicystic Dysplastic Kidney Disease: A Comprehensive Approach.

Multicystic dysplastic kidney (MCDK) is a congenital renal disease characterized by variable-sized noncommunicative cysts, impeding parenchymal development and functionality. Renal capabilities are relative to the functionality of the contralateral kidney and response to management. Unilateral and isolated cases are often asymptomatic with more positive outcomes, while severe bilateral derangements have a high mortality rate. We present a case of left-sided MCDK and right-sided renal dysplasia diagnosed at a nontertiary center. In addition, we offer a review of the epidemiology, epigenetics, and pathophysiology of MCDK. A concise discussion of prenatal, intrapartum, and postnatal renal function surveillance methods is presented to assist neonatal healthcare providers in collaborating with pediatric nephrology and urology specialists.

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