母亲的挣扎:产后子痫前期并发三血管自发性冠状动脉夹层。

IF 0.5 Q3 MEDICINE, GENERAL & INTERNAL
Oxford Medical Case Reports Pub Date : 2024-10-15 eCollection Date: 2024-10-01 DOI:10.1093/omcr/omae120
Branco G M Bettinotti, Mickias B Tegegn, Victor Razuk, Som Bailey, Rowena Hann, Cesar Mendoza, Marian T Calfa, Rosario A Colombo
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引用次数: 0

摘要

自发性冠状动脉夹层(SCAD)是年轻女性急性冠状动脉综合征的重要病因,尤其是在产后。妊娠相关性 SCAD(P-SCAD)是一种侵袭性亚型,常伴有多血管夹层、左心室功能减退和较高的死亡率。在此,我们介绍了一例罕见的产后先兆子痫并发多血管 SCAD 的病例,患者是一名 40 岁的海地黑人多产妇。诊断是通过冠状动脉造影确定的,造影显示左前降支、左冠状动脉和右冠状动脉自发夹层。鉴于患者血流动力学保持稳定,无需进行经皮冠状动脉介入治疗。住院期间,她反复出现心绞痛症状,在使用氯吡格雷后症状得到控制。目前对 P-SCAD 的病理生理学尚不十分清楚,认为与血流动力学应激状态加剧和激素波动有关。先兆子痫作为风险因素的作用仍未明确,值得进一步研究。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
A Mother's struggle: postpartum preeclampsia complicated by triple vessel spontaneous coronary artery dissection.

Spontaneous coronary artery dissection (SCAD) is an important cause of acute coronary syndrome among young women, especially in the postpartum period. Pregnancy-Associated SCAD (P-SCAD), an aggressive subtype, frequently involves multi-vessel dissection, decreased left ventricular function, and higher mortality. Here we present a rare case of postpartum pre-eclampsia complicated by multi-vessel SCAD in a 40-year-old multiparous Haitian black woman. Diagnosis was established with coronary angiography which revealed spontaneous dissection of the left anterior descendant, left circumflex, and right coronary arteries. Given the patient remained hemodynamically stable no percutaneous coronary intervention was indicated. She experienced recurrent anginal symptoms during her hospitalization that were managed with the addition of clopidogrel. The pathophysiology of P-SCAD is not well understood and thought to be related to an increased state of hemodynamic stress and hormonal fluctuation. The role of pre-eclampsia as a risk factor remains poorly defined and warrants further investigation.

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来源期刊
Oxford Medical Case Reports
Oxford Medical Case Reports MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
125
审稿时长
19 weeks
期刊介绍: Oxford Medical Case Reports (OMCR) is an open access, peer-reviewed online journal publishing original and educationally valuable case reports that expand the field of medicine. The journal covers all medical specialities including cardiology, rheumatology, nephrology, oncology, neurology, and reproduction, comprising a comprehensive resource for physicians in all fields and at all stages of training. Oxford Medical Case Reports deposits all articles in PubMed Central (PMC). Physicians and researchers can find your work through PubMed , helping you reach the widest possible audience. The journal is also indexed in the Web of Science Core Collection . Oxford Medical Case Reports publishes case reports under the following categories: Allergy Audiovestibular medicine Cardiology and cardiovascular systems Critical care medicine Dermatology Emergency medicine Endocrinology and metabolism Gastroenterology and hepatology Geriatrics and gerontology Haematology Immunology Infectious diseases and tropical medicine Medical disorders in pregnancy Medical ophthalmology Nephrology Neurology Oncology Paediatrics Pain Palliative medicine Pharmacology and pharmacy Psychiatry Radiology, nuclear medicine, and medical imaging Respiratory disorders Rheumatology Sexual and reproductive health Sports Medicine Substance abuse.
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