巨噬细胞的细胞周期

Q4 Biochemistry, Genetics and Molecular Biology

Results and Problems in Cell Differentiation Pub Date : 2024-01-01 DOI:10.1007/978-3-031-65944-7_4

Louis Dillac, Leon El Dika, Rahim Ullah, Jacek Z Kubiak, Malgorzata Kloc

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引用次数: 0

摘要

巨噬细胞是动态的、可塑性的免疫细胞，对组织稳态和病原体防御至关重要。它们的细胞周期调节受内在和外在信号的影响很大，有利于对感染和组织损伤做出快速反应。细胞周期失调会导致癌症和艾滋病等疾病。本章重点介绍巨噬细胞细胞周期中对开发靶向疗法至关重要的几个方面。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Macrophage Cell Cycle.

Macrophages are dynamic and plastic immune cells essential for tissue homeostasis and pathogen defense. Their cell cycle regulation is highly influenced by intrinsic and extrinsic signals facilitating rapid responses to infections and tissue damage. Dysregulation of their cell cycle leads to diseases like cancer and HIV. This chapter highlights aspects of the macrophage cell cycle crucial for the development of targeted therapies.

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来源期刊

Results and Problems in Cell Differentiation Biochemistry, Genetics and Molecular Biology-Developmental Biology

CiteScore

1.90

自引率

0.00%

发文量

期刊介绍： Results and Problems in Cell Differentiation is an up-to-date book series that presents and explores selected questions of cell and developmental biology. Each volume focuses on a single, well-defined topic. Reviews address basic questions and phenomena, but also provide concise information on the most recent advances. Together, the volumes provide a valuable overview of this exciting and dynamically expanding field.