儿童和青少年果糖和纤维摄入量以及体育锻炼与非酒精性脂肪肝的关系:一项横断面研究。

IF 1.9 Q3 NUTRITION & DIETETICS
Camellia Akhgarjand, Mahdieh Entezarian, Simin Samavat, Aryan Tavakoli, Aliarash Anoushirvani, Golaleh Asghari, Emad Yusbashian, Pooneh Dehghan, Parvin Mirmiran, Hossein Imani
{"title":"儿童和青少年果糖和纤维摄入量以及体育锻炼与非酒精性脂肪肝的关系:一项横断面研究。","authors":"Camellia Akhgarjand, Mahdieh Entezarian, Simin Samavat, Aryan Tavakoli, Aliarash Anoushirvani, Golaleh Asghari, Emad Yusbashian, Pooneh Dehghan, Parvin Mirmiran, Hossein Imani","doi":"10.1186/s40795-024-00943-w","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>Non-alcoholic fatty liver disease (NAFLD) is emerging as the most prevalent liver disease in overweight and obese children. While no cure exists, dietary and lifestyle modifications have been shown to improve the condition. This study investigates the relationship between fructose and fiber consumption, physical activity, and NAFLD in children.</p><p><strong>Methods: </strong>A cross-sectional study was conducted on 378 overweight and obese children aged 6-13 years. NAFLD diagnosis was confirmed via ultrasound, and dietary intake was assessed using a 147-item food frequency questionnaire (FFQ). Physical activity was evaluated using the Modifiable Activity Questionnaire (MAQ). Multivariable logistic regression models were applied to determine the associations.</p><p><strong>Results: </strong>After excluding 53 participants due to incomplete data, 325 were included in the final analysis. The mean age was 9.2 ± 1.7 years, and 35% had NAFLD. No significant association was found between fructose intake and NAFLD (OR: 0.67, 95% CI: 0.35-1.29, P = 0.221). However, higher intake of legume fiber (OR: 0.48, 95% CI: 0.26-0.90, P = 0.03) and nut fiber (OR: 0.52, 95% CI: 0.28-0.95, P = 0.04) was significantly associated with a reduced risk of NAFLD. Physical activity showed a trend towards reduced NAFLD risk but was not statistically significant after adjustments (OR: 0.53, 95% CI: 0.22-1.04, P = 0.07).</p><p><strong>Conclusions: </strong>While fructose intake was not significantly linked to NAFLD in this population, fiber from legumes and nuts appeared protective. Further prospective studies are needed to confirm these findings and clarify the role of physical activity in NAFLD prevention.</p>","PeriodicalId":36422,"journal":{"name":"BMC Nutrition","volume":null,"pages":null},"PeriodicalIF":1.9000,"publicationDate":"2024-10-21","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11494766/pdf/","citationCount":"0","resultStr":"{\"title\":\"The association of fructose and fiber consumption and physical activity with non-alcoholic fatty liver disease in children and adolescents: a cross-sectional study.\",\"authors\":\"Camellia Akhgarjand, Mahdieh Entezarian, Simin Samavat, Aryan Tavakoli, Aliarash Anoushirvani, Golaleh Asghari, Emad Yusbashian, Pooneh Dehghan, Parvin Mirmiran, Hossein Imani\",\"doi\":\"10.1186/s40795-024-00943-w\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>Non-alcoholic fatty liver disease (NAFLD) is emerging as the most prevalent liver disease in overweight and obese children. While no cure exists, dietary and lifestyle modifications have been shown to improve the condition. This study investigates the relationship between fructose and fiber consumption, physical activity, and NAFLD in children.</p><p><strong>Methods: </strong>A cross-sectional study was conducted on 378 overweight and obese children aged 6-13 years. NAFLD diagnosis was confirmed via ultrasound, and dietary intake was assessed using a 147-item food frequency questionnaire (FFQ). Physical activity was evaluated using the Modifiable Activity Questionnaire (MAQ). Multivariable logistic regression models were applied to determine the associations.</p><p><strong>Results: </strong>After excluding 53 participants due to incomplete data, 325 were included in the final analysis. The mean age was 9.2 ± 1.7 years, and 35% had NAFLD. No significant association was found between fructose intake and NAFLD (OR: 0.67, 95% CI: 0.35-1.29, P = 0.221). However, higher intake of legume fiber (OR: 0.48, 95% CI: 0.26-0.90, P = 0.03) and nut fiber (OR: 0.52, 95% CI: 0.28-0.95, P = 0.04) was significantly associated with a reduced risk of NAFLD. Physical activity showed a trend towards reduced NAFLD risk but was not statistically significant after adjustments (OR: 0.53, 95% CI: 0.22-1.04, P = 0.07).</p><p><strong>Conclusions: </strong>While fructose intake was not significantly linked to NAFLD in this population, fiber from legumes and nuts appeared protective. Further prospective studies are needed to confirm these findings and clarify the role of physical activity in NAFLD prevention.</p>\",\"PeriodicalId\":36422,\"journal\":{\"name\":\"BMC Nutrition\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.9000,\"publicationDate\":\"2024-10-21\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11494766/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"BMC Nutrition\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1186/s40795-024-00943-w\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NUTRITION & DIETETICS\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"BMC Nutrition","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1186/s40795-024-00943-w","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NUTRITION & DIETETICS","Score":null,"Total":0}
引用次数: 0

摘要

背景:非酒精性脂肪肝正在成为超重和肥胖儿童最常见的肝病。虽然目前尚无根治方法,但饮食和生活方式的改变已被证明可改善病情。本研究调查了儿童果糖和纤维摄入量、体力活动与非酒精性脂肪肝之间的关系:方法:本研究对 378 名 6-13 岁超重和肥胖儿童进行了横断面研究。非酒精性脂肪肝通过超声波确诊,饮食摄入量通过 147 项食物频率问卷(FFQ)进行评估。体力活动采用可改变活动量问卷(MAQ)进行评估。采用多变量逻辑回归模型确定相关性:由于数据不完整,排除了 53 名参与者,最终分析纳入了 325 名参与者。平均年龄为(9.2 ± 1.7)岁,35%患有非酒精性脂肪肝。果糖摄入量与非酒精性脂肪肝之间没有明显关联(OR:0.67,95% CI:0.35-1.29,P = 0.221)。然而,摄入较多的豆类纤维(OR:0.48,95% CI:0.26-0.90,P = 0.03)和坚果纤维(OR:0.52,95% CI:0.28-0.95,P = 0.04)与非酒精性脂肪肝风险的降低有明显关系。体育锻炼有降低非酒精性脂肪肝风险的趋势,但经调整后无统计学意义(OR:0.53,95% CI:0.22-1.04,P = 0.07):结论:在这一人群中,果糖摄入量与非酒精性脂肪肝的关系不大,但豆类和坚果中的纤维似乎具有保护作用。需要进一步的前瞻性研究来证实这些发现,并明确体育锻炼在预防非酒精性脂肪肝中的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The association of fructose and fiber consumption and physical activity with non-alcoholic fatty liver disease in children and adolescents: a cross-sectional study.

Background: Non-alcoholic fatty liver disease (NAFLD) is emerging as the most prevalent liver disease in overweight and obese children. While no cure exists, dietary and lifestyle modifications have been shown to improve the condition. This study investigates the relationship between fructose and fiber consumption, physical activity, and NAFLD in children.

Methods: A cross-sectional study was conducted on 378 overweight and obese children aged 6-13 years. NAFLD diagnosis was confirmed via ultrasound, and dietary intake was assessed using a 147-item food frequency questionnaire (FFQ). Physical activity was evaluated using the Modifiable Activity Questionnaire (MAQ). Multivariable logistic regression models were applied to determine the associations.

Results: After excluding 53 participants due to incomplete data, 325 were included in the final analysis. The mean age was 9.2 ± 1.7 years, and 35% had NAFLD. No significant association was found between fructose intake and NAFLD (OR: 0.67, 95% CI: 0.35-1.29, P = 0.221). However, higher intake of legume fiber (OR: 0.48, 95% CI: 0.26-0.90, P = 0.03) and nut fiber (OR: 0.52, 95% CI: 0.28-0.95, P = 0.04) was significantly associated with a reduced risk of NAFLD. Physical activity showed a trend towards reduced NAFLD risk but was not statistically significant after adjustments (OR: 0.53, 95% CI: 0.22-1.04, P = 0.07).

Conclusions: While fructose intake was not significantly linked to NAFLD in this population, fiber from legumes and nuts appeared protective. Further prospective studies are needed to confirm these findings and clarify the role of physical activity in NAFLD prevention.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
BMC Nutrition
BMC Nutrition Medicine-Public Health, Environmental and Occupational Health
CiteScore
2.80
自引率
0.00%
发文量
131
审稿时长
15 weeks
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信