利用长序列测序进行疟疾基因组监测的进展。

IF 7 1区医学 Q1 PARASITOLOGY

Trends in parasitology Pub Date : 2024-11-01 Epub Date: 2024-10-16 DOI:10.1016/j.pt.2024.10.001

Julia Zerebinski, David F Plaza

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引用次数: 0

摘要

Girgis 等人和 de Cesare 等人最近的研究有望利用廉价、便携的长线程扩增序列技术推进疟疾基因组监测。这些技术可以快速鉴定干血斑中的抗药性标记、抗原多样性和诊断目标位点，为疟疾流行地区的监测提供新的工具，并为更有效地防治疟疾的干预措施提供信息。

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Progress in malaria genomic surveillance using long-read sequencing.

Recent studies by Girgis et al. and de Cesare et al. promise to advance malaria genomic surveillance using inexpensive and portable long-read amplicon-sequencing technologies. These technologies allow rapid characterization of drug-resistance markers, antigenic diversity, and diagnostic target loci from dried blood spots, providing new tools for surveillance in endemic regions and informing interventions to combat malaria more effectively.

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来源期刊

Trends in parasitology 医学-寄生虫学

CiteScore

14.00

自引率

3.10%

发文量

148

审稿时长

6-12 weeks

期刊介绍： Since its inception as Parasitology Today in 1985, Trends in Parasitology has evolved into a highly esteemed review journal of global significance, reflecting the importance of medical and veterinary parasites worldwide. The journal serves as a hub for communication among researchers across all disciplines of parasitology, encompassing endoparasites, ectoparasites, transmission vectors, and susceptible hosts. Each monthly issue of Trends in Parasitology offers authoritative, cutting-edge, and yet accessible review articles, providing a balanced and comprehensive overview, along with opinion pieces offering personal and novel perspectives. Additionally, the journal publishes a variety of short articles designed to inform and stimulate thoughts in a lively and widely-accessible manner. These include Science & Society (discussing the interface between parasitology and the general public), Spotlight (highlighting recently published research articles), Forum (presenting single-point hypotheses), Parasite/Vector of the Month (featuring a modular display of the selected species), Letter (providing responses to recent articles in Trends in Parasitology), and Trendstalk (conducting interviews). Please note that the journal exclusively publishes literature reviews based on published data, with systematic reviews, meta-analysis, and unpublished primary research falling outside our scope.