{"title":"2024 年埃塞俄比亚妊娠期高血压疾病的负担、风险因素、产妇产后和分娩结局：系统回顾和荟萃分析。","authors":"Astawus Alemayehu, Abebaw Demissie, Ibsa Ibrahim, Addisalem Geremew, Feysal Mohammed, Mogos Gudeta, Lamessa Oljira, Yadeta Dessie, Nega Assefa","doi":"10.1177/20503121241274741","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>This review aimed to report the estimated pooled level of prevalence, risk factors, and birth outcome of hypertensive disorder of pregnancy in Ethiopia, in 2024.</p><p><strong>Design: </strong>A systematic review and meta-analysis approach was utilized.</p><p><strong>Data sources and methods: </strong>PubMed/MEDLINE, Google Scholar, African Index Medicus, Web of Science, and CINHAL (EBSCO) search was carried out. The result was written according to the PRISMA-updated guidelines. To estimate the pooled prevalence and effect sizes, a random-effect model was used. Heterogeneity was assessed and investigated using <i>I</i> <sup>2</sup> test statistics and meta-regression, respectively. Publication bias was assessed using funnel plot and Egger's test statistics. Statistical tests result at <i>p</i>-value < 0.05 were declared as having significance.</p><p><strong>Result: </strong>From a total of 52 primary studies with a total sample size of 269, 158 were included in this systematic review and meta-analysis. The pooled prevalence of hypertensive disorder in pregnancy was 8%. Egger's test statistics (<i>p</i> = 0.8013) showed there is no publication bias. Having a history of kidney disease (AOR: 3.47), being rural resident (AOR: 2.5), having fruit intake during pregnancy (AOR: 0.39), being overweight (AOR: 2.24), and having multiple pregnancy (AOR: 2.1) were found to have a significant association with hypertensive disorder of pregnancy.</p><p><strong>Conclusion: </strong>Overall, the level of prevalence of hypertensive disorders of pregnancy in Ethiopia was significantly increasing. Having a history of kidney disease was found to have a strong association with hypertensive disorders of pregnancy among factors. The most common or dominant adverse maternal and childbirth outcomes were low birth weight, preterm birth, fifth minute low APGAR score; and eclampsia, hemolysis, elevated liver enzymes, and low platelets syndrome, and acute kidney injury. The governments and other stakeholders should work to broaden and strengthen the existing maternal and child health (MCH) practice by incorporating all possible risk factors of hypertensive disorders of pregnancy in MCH guidelines. In addition, a large-scale study is required that considers those important missed variables, especially, in the eastern part of Ethiopia.</p>","PeriodicalId":21398,"journal":{"name":"SAGE Open Medicine","volume":"12 ","pages":"20503121241274741"},"PeriodicalIF":2.3000,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11483801/pdf/","citationCount":"0","resultStr":"{\"title\":\"Burden, risk factors, and maternal postpartum and birth outcomes of hypertensive disorder of pregnancy in Ethiopia, 2024: A systematic review and meta-analysis.\",\"authors\":\"Astawus Alemayehu, Abebaw Demissie, Ibsa Ibrahim, Addisalem Geremew, Feysal Mohammed, Mogos Gudeta, Lamessa Oljira, Yadeta Dessie, Nega Assefa\",\"doi\":\"10.1177/20503121241274741\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>This review aimed to report the estimated pooled level of prevalence, risk factors, and birth outcome of hypertensive disorder of pregnancy in Ethiopia, in 2024.</p><p><strong>Design: </strong>A systematic review and meta-analysis approach was utilized.</p><p><strong>Data sources and methods: </strong>PubMed/MEDLINE, Google Scholar, African Index Medicus, Web of Science, and CINHAL (EBSCO) search was carried out. The result was written according to the PRISMA-updated guidelines. To estimate the pooled prevalence and effect sizes, a random-effect model was used. Heterogeneity was assessed and investigated using <i>I</i> <sup>2</sup> test statistics and meta-regression, respectively. Publication bias was assessed using funnel plot and Egger's test statistics. Statistical tests result at <i>p</i>-value < 0.05 were declared as having significance.</p><p><strong>Result: </strong>From a total of 52 primary studies with a total sample size of 269, 158 were included in this systematic review and meta-analysis. The pooled prevalence of hypertensive disorder in pregnancy was 8%. Egger's test statistics (<i>p</i> = 0.8013) showed there is no publication bias. Having a history of kidney disease (AOR: 3.47), being rural resident (AOR: 2.5), having fruit intake during pregnancy (AOR: 0.39), being overweight (AOR: 2.24), and having multiple pregnancy (AOR: 2.1) were found to have a significant association with hypertensive disorder of pregnancy.</p><p><strong>Conclusion: </strong>Overall, the level of prevalence of hypertensive disorders of pregnancy in Ethiopia was significantly increasing. Having a history of kidney disease was found to have a strong association with hypertensive disorders of pregnancy among factors. The most common or dominant adverse maternal and childbirth outcomes were low birth weight, preterm birth, fifth minute low APGAR score; and eclampsia, hemolysis, elevated liver enzymes, and low platelets syndrome, and acute kidney injury. The governments and other stakeholders should work to broaden and strengthen the existing maternal and child health (MCH) practice by incorporating all possible risk factors of hypertensive disorders of pregnancy in MCH guidelines. In addition, a large-scale study is required that considers those important missed variables, especially, in the eastern part of Ethiopia.</p>\",\"PeriodicalId\":21398,\"journal\":{\"name\":\"SAGE Open Medicine\",\"volume\":\"12 \",\"pages\":\"20503121241274741\"},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-10-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11483801/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"SAGE Open Medicine\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1177/20503121241274741\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q2\",\"JCRName\":\"MEDICINE, GENERAL & INTERNAL\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"SAGE Open Medicine","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1177/20503121241274741","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q2","JCRName":"MEDICINE, GENERAL & INTERNAL","Score":null,"Total":0}
引用次数: 0
摘要
目的：本综述旨在报告 2024 年埃塞俄比亚妊娠期高血压疾病的发病率、风险因素和分娩结果的估计汇总水平：本综述旨在报告 2024 年埃塞俄比亚妊娠期高血压疾病的患病率、风险因素和分娩结局的估计汇总水平：设计：采用系统回顾和荟萃分析方法：进行了 PubMed/MEDLINE、Google Scholar、African Index Medicus、Web of Science 和 CINHAL（EBSCO）检索。结果按照 PRISMA 更新指南撰写。采用随机效应模型估算汇总的流行率和效应大小。异质性分别采用 I 2 检验统计和元回归进行评估和研究。使用漏斗图和 Egger 检验统计量评估发表偏倚。统计检验结果为 p 值 结果：本系统综述和荟萃分析共纳入了 52 项主要研究，样本量共计 269 个，其中 158 个被纳入。合并后的妊娠期高血压患病率为 8%。Egger 检验统计（P = 0.8013）表明不存在发表偏倚。有肾病史（AOR：3.47）、农村居民（AOR：2.5）、孕期水果摄入量（AOR：0.39）、超重（AOR：2.24）和多胎妊娠（AOR：2.1）与妊娠期高血压疾病有显著相关性：结论：总体而言，埃塞俄比亚妊娠期高血压疾病的发病率呈明显上升趋势。在各种因素中，有肾病史与妊娠高血压疾病有密切关系。最常见或最主要的不良孕产后果是低出生体重、早产、APGAR 评分低五分；子痫、溶血、肝酶升高、血小板低综合征和急性肾损伤。各国政府和其他利益相关者应努力扩大和加强现有的母婴保健实践，将妊娠高血压疾病的所有可能风险因素纳入母婴保健指南。此外，还需要开展一项大规模的研究，考虑那些被遗漏的重要变量，尤其是在埃塞俄比亚东部地区。
Burden, risk factors, and maternal postpartum and birth outcomes of hypertensive disorder of pregnancy in Ethiopia, 2024: A systematic review and meta-analysis.
Objectives: This review aimed to report the estimated pooled level of prevalence, risk factors, and birth outcome of hypertensive disorder of pregnancy in Ethiopia, in 2024.
Design: A systematic review and meta-analysis approach was utilized.
Data sources and methods: PubMed/MEDLINE, Google Scholar, African Index Medicus, Web of Science, and CINHAL (EBSCO) search was carried out. The result was written according to the PRISMA-updated guidelines. To estimate the pooled prevalence and effect sizes, a random-effect model was used. Heterogeneity was assessed and investigated using I2 test statistics and meta-regression, respectively. Publication bias was assessed using funnel plot and Egger's test statistics. Statistical tests result at p-value < 0.05 were declared as having significance.
Result: From a total of 52 primary studies with a total sample size of 269, 158 were included in this systematic review and meta-analysis. The pooled prevalence of hypertensive disorder in pregnancy was 8%. Egger's test statistics (p = 0.8013) showed there is no publication bias. Having a history of kidney disease (AOR: 3.47), being rural resident (AOR: 2.5), having fruit intake during pregnancy (AOR: 0.39), being overweight (AOR: 2.24), and having multiple pregnancy (AOR: 2.1) were found to have a significant association with hypertensive disorder of pregnancy.
Conclusion: Overall, the level of prevalence of hypertensive disorders of pregnancy in Ethiopia was significantly increasing. Having a history of kidney disease was found to have a strong association with hypertensive disorders of pregnancy among factors. The most common or dominant adverse maternal and childbirth outcomes were low birth weight, preterm birth, fifth minute low APGAR score; and eclampsia, hemolysis, elevated liver enzymes, and low platelets syndrome, and acute kidney injury. The governments and other stakeholders should work to broaden and strengthen the existing maternal and child health (MCH) practice by incorporating all possible risk factors of hypertensive disorders of pregnancy in MCH guidelines. In addition, a large-scale study is required that considers those important missed variables, especially, in the eastern part of Ethiopia.
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