癫痫患者吞咽困难:无声的敌人

IF 2.3 Q3 CLINICAL NEUROLOGY
Neurology. Clinical practice Pub Date : 2025-02-01 Epub Date: 2024-10-08 DOI:10.1212/CPJ.0000000000200362
James W Wheless, Brooke Richardson, Clio Rubinos, Raymond Faught, Marry Vuong
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引用次数: 0

摘要

回顾的目的:吞咽困难或吞咽困难在全球范围内影响着许多人,可导致生活质量下降和部分服药依从性降低,尤其是癫痫患者。医护人员和患者对吞咽困难也缺乏认识和了解。本综述探讨了吞咽困难与癫痫治疗之间的相互作用,以及优化诊断和干预的可能性:吞咽困难虽然是一种常见病,但往往诊断不足或误诊。治疗吞咽困难需要对患者和护理人员进行药物管理技巧、生活方式改变方面的教育,并与多学科医疗团队合作。此外,还有几种方法可以通过使用技术、问卷调查和询问探究性问题来筛查和评估吞咽困难。在癫痫患者中,吞咽困难可能会使患者难以或无法吞咽某些配方的抗癫痫药物(ASMs)--因此,如果无法停药,就需要采取量身定制的管理策略。可溶性、液体、颗粒状或粉末状等替代制剂已被认为是解决因吞咽困难导致的部分服药问题的重要选择。为解决这一问题,已开发出各种调查问卷和评估方法来发现吞咽困难。在使用替代 ASM 制剂时,必须考虑到每个人的可选方案。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Dysphagia in Epilepsy Patients: The Silent Enemy.

Purpose of review: Dysphagia, or difficulty swallowing, affects several individuals globally and can contribute to a reduced quality of life and partial medication adherence, especially in patients with epilepsy. There is also a lack of awareness and understanding of dysphagia among both health care providers and patients. This review examines the interplay between dysphagia and epilepsy treatment and the potential for optimizing diagnosis and intervention.

Recent findings: Dysphagia, although a prevalent condition, is often underdiagnosed or misdiagnosed. Managing dysphagia involves patient and caregiver education on medication management techniques, lifestyle changes, and collaboration with a multidisciplinary health care team. There are also several modalities to screen and evaluate for dysphagia by using technology, using questionnaires, and asking probing questions. In patients with epilepsy, dysphagia can make swallowing certain formulations of antiseizure medications (ASMs) difficult or impossible-so, there is a need for tailored management strategies if discontinuing the medication is not feasible. Alternative formulations such as soluble, liquid, granular, or powder alternatives have been recognized as valuable options in addressing partial adherence due to dysphagia.

Summary: Patients with dysphagia may have varying symptoms, making it challenging for clinicians to accurately identify the condition. To address this issue, various questionnaires and assessments have been developed to uncover swallowing difficulties. Administration of alternate ASM formulations must consider options available for each individual.

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来源期刊
Neurology. Clinical practice
Neurology. Clinical practice CLINICAL NEUROLOGY-
CiteScore
4.00
自引率
0.00%
发文量
77
期刊介绍: Neurology® Genetics is an online open access journal publishing peer-reviewed reports in the field of neurogenetics. The journal publishes original articles in all areas of neurogenetics including rare and common genetic variations, genotype-phenotype correlations, outlier phenotypes as a result of mutations in known disease genes, and genetic variations with a putative link to diseases. Articles include studies reporting on genetic disease risk, pharmacogenomics, and results of gene-based clinical trials (viral, ASO, etc.). Genetically engineered model systems are not a primary focus of Neurology® Genetics, but studies using model systems for treatment trials, including well-powered studies reporting negative results, are welcome.
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