吸烟对腰椎减压术后患者报告结果的影响:优质结果数据库分析。

IF 2.9 2区 医学 Q2 CLINICAL NEUROLOGY
Mladen Djurasovic, R Kirk Owens, Leah Y Carreon, Jeffrey L Gum, Erica F Bisson, Mohamad Bydon, Steven D Glassman
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引用次数: 0

摘要

目的:吸烟已被证明会对脊柱健康和脊柱融合术的效果产生负面影响。关于吸烟是否会对腰椎减压术后患者的疗效产生负面影响,已发表的报告显示了相互矛盾的数据。本研究旨在调查吸烟是否会影响因椎管狭窄或椎间盘突出而接受腰椎减压术的患者的治疗效果:方法:在质量结果数据库中查询了接受一或两级腰椎减压术而未行融合术的椎管狭窄症或腰椎间盘突出症患者。所有患者都进行了术前和 12 个月的疗效测量,并被分为非吸烟者和当前吸烟者两组。比较了两组患者的治疗效果,以及达到数字评分量表(NRS)腰腿痛评分和奥斯韦特里残疾指数(ODI)最小临床意义差异(MCID)阈值的患者比例:在 17271 名患者中,14233 人为非吸烟者,3038 人为当前吸烟者。吸烟者的基线NRS腰痛和腿痛、ODI和EQ-5D评分较差,腰椎减压术后所有指标的改善程度都略低(P≤0.009),但变化基本相似,而且有很高比例的患者达到了NRS腰痛(78%非吸烟者 vs 75%吸烟者)、NRS腿痛(79%非吸烟者 vs 73%吸烟者)和ODI(74%非吸烟者 vs 68%吸烟者)的MCID阈值。对倾向匹配队列进行比较后发现,吸烟者与非吸烟者的治疗效果没有任何差异:结论:在因椎管狭窄或椎间盘突出而接受腰椎减压术的患者中,吸烟者的疗效改善程度略低于不吸烟者,但两组患者中均有很高比例的患者通过手术获得了有意义的改善。虽然应大力鼓励所有患者戒烟,但不应拒绝为吸烟者提供腰椎管狭窄症和椎间盘突出症的腰椎减压手术。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The impact of smoking on patient-reported outcomes following lumbar decompression: an analysis of the Quality Outcomes Database.

Objective: Smoking has been shown to negatively impact spinal health, as well as the outcomes of spinal fusion. Published reports show conflicting data regarding whether smoking negatively impacts patient outcomes following lumbar decompression. The objective of this study was to investigate whether smoking affects the outcomes of patients undergoing lumbar decompression for spinal stenosis or herniated disc.

Methods: The Quality Outcomes Database was queried for patients with spinal stenosis or lumbar disc herniation who underwent one- or two-level lumbar decompression without fusion. All patients had preoperative and 12-month outcome measures and were divided into groups of nonsmokers and current smokers. Outcomes were compared between the two groups, as well as the percentage of patients reaching the minimal clinically important difference (MCID) threshold for numeric rating scale (NRS) back and leg pain scores and the Oswestry Disability Index (ODI).

Results: Of 17,271 patients, 14,233 were nonsmokers and 3038 were current smokers. Smokers had worse baseline NRS back and leg pain, ODI, and EQ-5D scores and experienced slightly less improvement in all measures following lumbar decompression (p ≤ 0.009), although changes were largely similar, and a high percentage of patients achieved the MCID thresholds for NRS back pain (78% nonsmokers vs 75% smokers), NRS leg pain (79% nonsmokers vs 73% smokers), and ODI (74% nonsmokers vs 68% smokers). Comparison of propensity-matched cohorts did not identify any difference in outcomes in smokers versus nonsmokers.

Conclusions: In patients undergoing lumbar decompression for spinal stenosis or herniated disc, smokers demonstrated slightly less improvement in outcomes compared with nonsmokers, and a high proportion of both groups achieved meaningful improvement with surgery. While smoking cessation should be strongly encouraged in all patients, lumbar decompression procedures for spinal stenosis and herniated disc should not be denied to smokers.

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来源期刊
Journal of neurosurgery. Spine
Journal of neurosurgery. Spine 医学-临床神经学
CiteScore
5.10
自引率
10.70%
发文量
396
审稿时长
6 months
期刊介绍: Primarily publish original works in neurosurgery but also include studies in clinical neurophysiology, organic neurology, ophthalmology, radiology, pathology, and molecular biology.
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