颈动脉支架治疗无症状颈动脉近端闭塞:可行性、安全性和结果分析。

IF 1.7 4区 医学 Q3 Medicine
Emre Can Çelebioğlu, Guilherme Dabus, Sena Bozer Uludağ, Ömer Arda Çetinkaya, Sena Ünal, Uğur Bengisun, Sadık Eryılmaz, Mine Hayriye Sorgun, İhsan Doğan, Şermin Atmaca, Evren Özçınar, Başak Ceyda Meço, Mustafa Bahadır İnan, Canan Togay Işıkay, Ahmet Rüçhan Akar, İskender Alaçayır, Sadık Bilgiç
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引用次数: 0

摘要

导言:颅外颈动脉内狭窄(EICS)是脑卒中的公认病因。颈动脉近闭塞(CNO),无论是否远端塌陷,都是 EICS 的一种罕见亚型,有关治疗必要性的数据相互矛盾。本研究旨在评估对有症状的 CNO 患者进行颈动脉支架植入术(CAS)的效果:这项回顾性研究获得了机构审查委员会(I06-420-23)的批准。获得了 2019 年 1 月至 2023 年 1 月的连续数据。65 名患者因症状性 CNO 接受了 66 次手术。CNO 的诊断是通过 DSA 图像做出的。治疗决定由多学科团队做出。记录并分析了患者数据,包括年龄、性别、临床表现、患侧、并发症(初始/随访)以及术前和术后的mRS评分:有症状的 CNO 患者中有 22 名女性和 43 名男性(平均年龄:71.52 ± 9.32 岁)。从出现症状到接受治疗的平均时间为 3.91 周 ± 3.74 周(0 至 20 周不等)。CAS 治疗后 30 天内共记录到 8 起事件,其中 5 起(7.7%)为脑过度灌注综合征(1 起导致出血),3 起(4.5%)为缺血性并发症。永久性神经功能缺损率为 6%,61 名患者(94%)的 mRS 评分在最后一次随访中保持不变。平均随访时间为 22.94 ± 16.67 个月(0.5 至 60 个月):我们的研究表明,对于症状复杂的 CNO 患者,CAS 是一种可行的选择,其永久性神经功能缺损的发生率是可以接受的。还需要进一步的研究来评估其安全性和长期疗效。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Carotid artery stenting for symptomatic carotid near occlusions: Feasibility, safety and outcome analysis.

Introduction: Extracranial internal carotid stenosis (EICS) is a well-established cause of stroke. Carotid near-occlusion (CNO), either distally collapsed or not, is a rare sub-type of EICS with conflicting data regarding the necessity for treatment. The aim of this study is to evaluate the results of carotid artery stenting (CAS) for patients with symptomatic CNOs.

Material and methods: Institutional review board (I06-420-23) approval was obtained for this retrospective study. Consecutive data from January 2019 to January 2023 was obtained. Sixty-five patients underwent 66 procedures for symptomatic CNOs. Diagnosis of CNOs were made with DSA images. Treatment decisions were made by a multidisciplinary team. Patient data including age, gender, clinical presentation, affected side, complications (initial/ follow-up), and pre and post mRS scores were recorded and analyzed.

Results: There were 22 female and 43 male patients with symptomatic CNOs (mean age: 71.52 ± 9.32 years). The mean time from symptom-to-treatment was 3.91 weeks ± 3.74 weeks (ranging from 0 to 20 weeks). There were eight events recorded in the 30 days period after CAS; five (7.7%) were cerebral hyperperfusion syndrome (one causing haemorrhage) and three (4.5%) ischemic complications. Permanent neurologic deficit rate was 6% and 61 patients (94%) mRS scores were unchanged during last follow-up. Mean follow-up period was 22.94 ± 16.67 months (ranging from 0.5 to 60 months).

Conclusion: Our study demonstrated that in the complex population of patients with symptomatic CNOs, CAS is a feasible option with acceptable rate of permanent neurologic deficits. Further studies are needed to assess its safety and long-term efficacy.

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来源期刊
CiteScore
2.80
自引率
11.80%
发文量
192
审稿时长
6-12 weeks
期刊介绍: Interventional Neuroradiology (INR) is a peer-reviewed clinical practice journal documenting the current state of interventional neuroradiology worldwide. INR publishes original clinical observations, descriptions of new techniques or procedures, case reports, and articles on the ethical and social aspects of related health care. Original research published in INR is related to the practice of interventional neuroradiology...
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