通过新一代测序鉴定候选骨髓捐献者的新型 HLA-DQB1*03:01:01:69 等位基因。

IF 5.9 4区医学 Q2 CELL BIOLOGY

HLA Pub Date : 2024-10-22 DOI:10.1111/tan.15741

Diamanto Kouniaki, Alexandra Tsirogianni

引用次数: 0

摘要

HLA-DQB1*03:01:01:69等位基因与HLA-DQB1*03:01:01:03等位基因的区别在于内含子2中的一个核苷酸替换。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Identification of the Novel HLA-DQB1*03:01:01:69 Allele in a Candidate Bone Marrow Donor by Next Generation Sequencing

The HLA-DQB1*03:01:01:69 allele differs from HLA-DQB1*03:01:01:03 by a single nucleotide substitution in intron 2.

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来源期刊

HLA Immunology and Microbiology-Immunology

CiteScore

3.00

自引率

28.80%

发文量

368

期刊介绍： HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.