在高海拔地区确诊患有支气管炎的婴儿下降对临床的影响:一项前瞻性多中心研究

IF 1.6 4区 医学 Q4 BIOPHYSICS
Anne Poirier, Amélie Basso, Sarah Bonnet-Ducrot, Ellen Katranji, Sophia Cherif-Alami, Sophie Chateigner-Coelsch, Manon Navarre, Cécile Ricard, Corentin Tanné
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引用次数: 0

摘要

普瓦里耶、安妮、阿梅莉-巴索、萨拉-邦内-杜克洛、艾伦-卡特兰吉、索菲亚-谢里夫-阿拉米、索菲亚-查蒂涅-科尔什、马农-纳瓦拉、塞西尔-里卡尔和科伦坦-坦内。在高海拔地区诊断出患有支气管炎的婴儿下降对临床的影响:一项前瞻性多中心研究。00:00-00, 2024.目的:本研究旨在评估在海拔 1,000 米以上确诊患有支气管炎的婴儿下降到较低海拔对临床的影响:我们在连续两个冬季(2022-2023 年和 2023-2024 年)进行了一项前瞻性多中心观察研究。由当地全科医生(GP)做出诊断,然后将年龄小于 1 岁且王氏呼吸评分(WRS)≥4 分的患者送往位于海拔较低地区的五个急诊科(ED)中的任何一个。比较了全科医生和急诊室记录的 WRS、外周血氧饱和度 (SpO2) 和呼吸频率 (RR)。结果:我们纳入了 74 名婴儿(59% 为女性,中位年龄为 5.4 [3.6-8.0] 个月)。与海拔 1,000 米以上的全科医生记录的中值相比,海拔较低的急诊室记录的 WRS(5.0 对 6.0,p = 0.002)、RR(50/分钟对 60/分钟,p = 0.001)和 SpO2(97.0% 对 91.5%,p < 0.001)的中值明显更好。结论对于在海拔 1,000 米以上地区确诊患有支气管炎的 1 岁以下婴儿,下降到较低海拔可明显改善其呼吸功能。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Clinical Effect of Descent in Infants with Bronchiolitis Diagnosed at Altitude: A Prospective Multicenter Study.

Poirier, Anne, Amélie Basso, Sarah Bonnet-Ducrot, Ellen Katranji, Sophia Cherif-Alami, Sophie Chateigner-Coelsch, Manon Navarre, Cécile Ricard, and Corentin Tanné. Clinical Effect of Descent in Infants with Bronchiolitis Diagnosed at Altitude: A Prospective Multicenter Study. High Alt Med Biol. 00:00-00, 2024. Objective: This study aims to assess the clinical impact of descending to a lower altitude in infants with bronchiolitis diagnosed at an altitude above 1,000 m. Methods: We performed a prospective, observational, multicenter study during two consecutive winters (2022-2023 and 2023-2024). The diagnosis was made by local general practitioners (GPs) who then sent the patients who were younger than 1 year and had a Wang respiratory score (WRS) ≥4 to any of the five emergency departments (EDs) located at lower altitudes. The WRS, peripheral oxygen saturation (SpO2), and respiratory rate (RR) recorded by the GPs and at the EDs were compared. Results: We included 74 infants (59% females, median age 5.4 [3.6-8.0] months). Compared with the median values recorded by the GPs at altitudes above 1,000 m, the median values at the lower-altitude EDs were significantly better for the WRS (5.0 vs. 6.0, p = 0.002), RR (50/min vs. 60/min, p = 0.001), and SpO2 (97.0% vs. 91.5%, p < 0.001). Conclusion: Descending to a lower altitude significantly improved respiratory function in infants younger than 1 year with bronchiolitis diagnosed at altitudes above 1,000 m.

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来源期刊
High altitude medicine & biology
High altitude medicine & biology 医学-公共卫生、环境卫生与职业卫生
CiteScore
3.80
自引率
9.50%
发文量
44
审稿时长
>12 weeks
期刊介绍: High Altitude Medicine & Biology is the only peer-reviewed journal covering the medical and biological issues that impact human life at high altitudes. The Journal delivers critical findings on the impact of high altitude on lung and heart disease, appetite and weight loss, pulmonary and cerebral edema, hypertension, dehydration, infertility, and other diseases. It covers the full spectrum of high altitude life sciences from pathology to human and animal ecology.
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