68Ga-DOTATATE和18F-FDG PET/CT在快速进展淋巴瘤中的应用

IF 9.6 3区医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING

Clinical Nuclear Medicine Pub Date : 2025-01-01 Epub Date: 2024-10-14 DOI:10.1097/RLU.0000000000005450

Ashwin Singh Parihar, Richard L Wahl, Amin H Jahromi

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引用次数: 0

摘要

摘要：以体生长激素受体为靶点的68Ga-DOTATATE PET/CT通常用于神经内分泌肿瘤的成像。然而，其他恶性肿瘤如淋巴瘤（包括霍奇金淋巴瘤和非霍奇金淋巴瘤）也有体生长抑素受体的表达，尽管表达程度低于神经内分泌肿瘤，因此在 68Ga-DOTATATE PET/CT 上也可能呈阳性。我们描述了一种表现不典型的侵袭性大 B 细胞淋巴瘤，该淋巴瘤初诊时模仿转移性神经内分泌肿瘤，68Ga-DOTATATE PET/CT 显示体生长激素受体高表达，随后的 18F-FDG PET/CT 显示病程进展迅速。

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68 Ga-DOTATATE and 18 F-FDG PET/CT in a Rapidly Progressing Lymphoma.

Abstract: 68 Ga-DOTATATE PET/CT targeting somatostatin receptors is commonly utilized in the imaging of neuroendocrine tumors. However, other malignancies such as lymphomas (both Hodgkin and non-Hodgkin) also have expression of somatostatin receptors, albeit to a lesser degree compared with the neuroendocrine tumors, and thus can be positive on a 68 Ga-DOTATATE PET/CT. We describe an atypical presentation of an aggressive large B-cell lymphoma mimicking a metastatic neuroendocrine tumor at initial presentation with high somatostatin receptor expression demonstrated on the 68 Ga-DOTATATE PET/CT and a rapidly progressing course on the subsequent 18 F-FDG PET/CT.

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来源期刊

Clinical Nuclear Medicine 医学-核医学

CiteScore

2.90

自引率

31.10%

发文量

1113

审稿时长

2 months

期刊介绍： Clinical Nuclear Medicine is a comprehensive and current resource for professionals in the field of nuclear medicine. It caters to both generalists and specialists, offering valuable insights on how to effectively apply nuclear medicine techniques in various clinical scenarios. With a focus on timely dissemination of information, this journal covers the latest developments that impact all aspects of the specialty. Geared towards practitioners, Clinical Nuclear Medicine is the ultimate practice-oriented publication in the field of nuclear imaging. Its informative articles are complemented by numerous illustrations that demonstrate how physicians can seamlessly integrate the knowledge gained into their everyday practice.