克劳森-卡斯反应在有机合成中的应用。

IF 7 2区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY

Chemical record Pub Date : 2024-10-21 DOI:10.1002/tcr.202400112

Pargat Singh, Abhijeet Singh, Dileep Kumar Singh, Mahendra Nath

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引用次数: 0

摘要

嵌入吡咯的有机分子因其在生物和材料领域的众多应用而备受重视。因此，多年来人们设计了多种合成策略来构建各种吡咯类似物。其中，克劳森-卡斯反应是合成各种 N-取代吡咯的最广泛使用的方案之一。本综述简要介绍了 Clauson-Kaas 反应及其改进，并详细说明了它在有机合成各个领域的应用。

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Applications of Clauson-Kaas Reaction in Organic Synthesis.

Pyrrole-embedded organic molecules received a considerable importance due to their numerous biological and material applications. Hence, several synthetic strategies have been devised for the construction of diverse pyrrole analogues over the years. Among these, the Clauson-Kaas reaction is one of the most widely used protocols for the synthesis of various N-substituted pyrroles. This review briefly describes the Clauson-Kaas reaction along with modifications and a detailed account on its applications in the various sectors of organic synthesis.

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来源期刊

Chemical record 化学-化学综合

CiteScore

11.00

自引率

3.00%

发文量

188

审稿时长

>12 weeks

期刊介绍： The Chemical Record (TCR) is a "highlights" journal publishing timely and critical overviews of new developments at the cutting edge of chemistry of interest to a wide audience of chemists (2013 journal impact factor: 5.577). The scope of published reviews includes all areas related to physical chemistry, analytical chemistry, inorganic chemistry, organic chemistry, polymer chemistry, materials chemistry, bioorganic chemistry, biochemistry, biotechnology and medicinal chemistry as well as interdisciplinary fields. TCR provides carefully selected highlight papers by leading researchers that introduce the author''s own experimental and theoretical results in a framework designed to establish perspectives with earlier and contemporary work and provide a critical review of the present state of the subject. The articles are intended to present concise evaluations of current trends in chemistry research to help chemists gain useful insights into fields outside their specialization and provide experts with summaries of recent key developments.