插入脑室腹腔分流术及其并发症的经济负担:菲律宾队列的研究结果。

IF 1.3 4区 医学 Q4 CLINICAL NEUROLOGY
Child's Nervous System Pub Date : 2024-12-01 Epub Date: 2024-10-21 DOI:10.1007/s00381-024-06651-x
Kevin Ivan P Chan, Abdelsimar T Omar, Kathleen Joy O Khu
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引用次数: 0

摘要

目的:插入脑室腹腔分流术(VPS)是治疗先天性脑积水的金标准,但有关发展中国家该手术费用的数据却很少。我们的目的是确定首次插入 VPS 的住院费用及其并发症(功能障碍和感染),并找出费用增加的预测因素:我们进行了一项回顾性队列研究,回顾了2015年至2019年期间在本院接受分流手术的先天性脑积水儿科患者的医疗和财务记录。我们还进行了多变量线性回归分析,以确定可预测费用的临床特征:125名患者共接受了230例脑脊液分流手术。插入 VPS 时的平均年龄为 9.8 个月(范围:7 天-8 年)。在中位 222 天的随访中,15 名患者(12%)出现分流功能障碍,25 名患者(20%)出现分流感染。所有患者的平均住院费用为 94,573.50 菲律宾比索(1815 美元)。费用较高的预测因素包括分流管感染(P 结论:该研究提供了有关住院费用的最新数据:该研究提供了发展中国家一家公立三级医院 VPS 植入术住院费用的最新数据。分流管感染、故障、肺炎、败血症和住院时间是费用的重要预测因素。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
The economic burden of ventriculoperitoneal shunt insertion and its complications: findings from a cohort in the Philippines.

Purpose: Ventriculoperitoneal shunt (VPS) insertion is the gold standard treatment for congenital hydrocephalus, but there is little data about the cost of this procedure in developing countries. We aimed to determine the in-hospitalization cost of initial VPS insertion and its complications (malfunction and infection) and identify predictors of increased cost.

Methods: We performed a retrospective cohort study by reviewing the medical and financial records of pediatric patients with congenital hydrocephalus and underwent shunt surgery at our institution between 2015 and 2019. We also performed multivariable linear regression analysis to determine clinical characteristics that were predictive of cost.

Results: A total of 230 cerebrospinal fluid diversion procedures were performed on 125 patients. The mean age during index VPS insertion was 9.8 months (range: 7 days-8 years). Over a median follow-up of 222 days, 15 patients (12%) developed shunt malfunction while 25 (20%) had a shunt infection. The mean in-hospitalization cost for all patients was PHP 94,573.50 (USD 1815). The predictors of higher cost included shunt infection (p < 0.001), shunt malfunction (p < 0.001), pneumonia (p = 0.006), sepsis (p = 0.004), and length of hospital stay (p = 0.005). Patients complicated by shunt infection had a higher mean cost (PHP 282,631.60; USD 5425) than uncomplicated patients (PHP 40,587.20 or USD 779; p < 0.001) and patients who had shunt malfunction (PHP 87,065.70 or USD 1671; p < 0.001).

Conclusion: The study provided current data on the in-hospitalization cost of VPS insertion in a public tertiary hospital in a developing country. Shunt infection, malfunction, pneumonia, sepsis, and length of hospital stay were significant predictors of cost.

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来源期刊
Child's Nervous System
Child's Nervous System 医学-临床神经学
CiteScore
3.00
自引率
7.10%
发文量
322
审稿时长
3 months
期刊介绍: The journal has been expanded to encompass all aspects of pediatric neurosciences concerning the developmental and acquired abnormalities of the nervous system and its coverings, functional disorders, epilepsy, spasticity, basic and clinical neuro-oncology, rehabilitation and trauma. Global pediatric neurosurgery is an additional field of interest that will be considered for publication in the journal.
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