治疗危及视力的糖尿病视网膜病变的当前研究和未来策略。

IF 3.7 3区 医学 Q1 OPHTHALMOLOGY
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引用次数: 0

摘要

糖尿病视网膜病变(DR)是糖尿病的主要眼部并发症,也是导致失明和视力损伤的主要原因,尤其是在工作年龄的成年人中。尽管糖尿病视网膜病变造成了巨大的医疗和经济负担,而且预计其全球发病率还会增加,尤其是在中低收入国家,但通过早期发现和及时干预,糖尿病视网膜病变造成的大部分视力损失仍然是可以预防的。本视角回顾了三个领域研究和创新的最新进展,首先是新型生物标志物(包括先进的成像模式、血清生物标志物和人工智能技术),用于预测DR的发病率和进展情况;其次是可转诊DR和视力威胁性DR(VTDR)的筛查和早期检测;最后是VTDR(包括糖尿病黄斑水肿(DME))的新型治疗策略,目的是减少糖尿病性失明。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Current research and future strategies for the management of vision-threatening diabetic retinopathy
Diabetic retinopathy (DR) is a major ocular complication of diabetes and the leading cause of blindness and visual impairment, particularly among adults of working-age adults. Although the medical and economic burden of DR is significant and its global prevalence is expected to increase, particularly in low- and middle-income countries, a large portion of vision loss caused by DR remains preventable through early detection and timely intervention. This perspective reviewed the latest developments in research and innovation in three areas, first novel biomarkers (including advanced imaging modalities, serum biomarkers, and artificial intelligence technology) to predict the incidence and progression of DR, second, screening and early detection of referable DR and vision-threatening DR (VTDR), and finally, novel therapeutic strategies for VTDR, including diabetic macular oedema (DME), with the goal of reducing diabetic blindness.
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来源期刊
CiteScore
8.10
自引率
18.20%
发文量
197
审稿时长
6 weeks
期刊介绍: The Asia-Pacific Journal of Ophthalmology, a bimonthly, peer-reviewed online scientific publication, is an official publication of the Asia-Pacific Academy of Ophthalmology (APAO), a supranational organization which is committed to research, training, learning, publication and knowledge and skill transfers in ophthalmology and visual sciences. The Asia-Pacific Journal of Ophthalmology welcomes review articles on currently hot topics, original, previously unpublished manuscripts describing clinical investigations, clinical observations and clinically relevant laboratory investigations, as well as .perspectives containing personal viewpoints on topics with broad interests. Editorials are published by invitation only. Case reports are generally not considered. The Asia-Pacific Journal of Ophthalmology covers 16 subspecialties and is freely circulated among individual members of the APAO’s member societies, which amounts to a potential readership of over 50,000.
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