评估前交叉韧带重建后两年内出现早期骨关节炎症状的标准:来自新西兰前交叉韧带登记处的数据。

IF 3.7 2区 医学 Q1 RHEUMATOLOGY
Matthew S Harkey, Jeffrey B Driban, David Todem, Christopher Kuenze, Armaghan Mahmoudian, Rebecca Meiring, Daniel O'Brien, Sarah Ward
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引用次数: 0

摘要

研究目的目的:确定前交叉韧带重建术(ACLR)后符合早期骨关节炎(OA)症状提示标准的患病率,并描述这些症状在 ACLR 术后头两年的纵向变化:我们分析了新西兰前交叉韧带注册中心(New Zealand ACL Registry)10231 名 14-40 岁患者的数据,这些患者在 ACLR 术后 6、12 和 24 个月完成了膝关节损伤和骨关节炎结果评分(KOOS)。在 4 个 KOOS 分量表中,至少有 2 个分量表的得分≤85% 即为提示早期 OA 的症状。纵向变化模式分为持续、缓解、新出现、不一致或三次就诊均无症状。使用广义估计方程比较了不同就诊时间、性别和年龄组的症状流行率和几率比(ORs),并使用多项式逻辑回归分析了症状变化的纵向模式:结果:ACLR术后6个月符合早期OA症状标准的比例为68%,12个月为54%,24个月为46%。纵向来看,33%的人症状持续,23%的人无症状,29%的人症状缓解,6%的人出现新症状,9%的人症状不一致。女性出现症状的几率一直较高(OR 范围:1.17-1.52)。年龄越大,出现症状的几率越高,尤其是在 6 个月内出现症状的几率(OR 范围:1.64-2.45):结论:ACLR术后两年内,提示早期OA的症状非常普遍,三分之一的患者症状持续存在。这些研究结果表明,症状更有可能持续存在,而不是新出现,这强调了早期识别和有针对性干预的重要性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Evaluating Criteria for Symptoms Suggestive of Early Osteoarthritis Over Two Years Post-Anterior Cruciate Ligament Reconstruction: Data From the New Zealand Anterior Cruciate Ligament Registry.

Objective: The objectives were to determine the prevalence of meeting criteria for symptoms suggestive of early osteoarthritis (OA) after anterior cruciate ligament reconstruction (ACLR) and to characterize the longitudinal changes in these symptoms during the first two years post-ACLR.

Methods: We analyzed data from 10,231 patients aged 14 to 40 years in the New Zealand ACL Registry who completed the Knee Injury and Osteoarthritis Outcome Score (KOOS) at 6, 12, and 24 months post-ACLR. Symptoms suggestive of early OA were defined as scoring ≤85% on at least two of four KOOS subscales. Longitudinal patterns of change were categorized as persistent, resolution, new, inconsistent, or no symptoms across the three visits. Prevalence and odds ratios (ORs) of symptoms were compared across visits, sex, and age groups using generalized estimating equations, and longitudinal patterns of symptom change were analyzed using multinomial logistic regression.

Results: Prevalence of meeting criteria of symptoms suggestive of early OA was 68% at 6 months, 54% at 12 months, and 46% at 24 months post-ACLR. Longitudinally, 33% had persistent symptoms, 23% had no symptoms, 29% showed symptom resolution, 6% developed new symptoms, and 9% had inconsistent symptoms. Women consistently showed higher odds of symptoms (OR range 1.17-1.52). Older age groups demonstrated higher odds of symptoms, particularly at 6 months (OR range 1.64-2.45).

Conclusion: Symptoms suggestive of early OA are highly prevalent within two years post-ACLR, with one third of patients experiencing persistent symptoms. These findings indicate that symptoms are more likely to persist rather than newly develop, emphasizing the importance of early identification and targeted interventions.

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来源期刊
CiteScore
9.40
自引率
6.40%
发文量
368
审稿时长
3-6 weeks
期刊介绍: Arthritis Care & Research, an official journal of the American College of Rheumatology and the Association of Rheumatology Health Professionals (a division of the College), is a peer-reviewed publication that publishes original research, review articles, and editorials that promote excellence in the clinical practice of rheumatology. Relevant to the care of individuals with rheumatic diseases, major topics are evidence-based practice studies, clinical problems, practice guidelines, educational, social, and public health issues, health economics, health care policy, and future trends in rheumatology practice.
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