En-Young N Wagner, Eva Maria Pichler, Mario Müller, Andrea Eisenhut, Ana Buadze, Yanhua Xu, Erich Seifritz, Marie-Pierre F Strippoli, Enrique Castelao, Setareh Ranjbar, Jennifer Glaus, Caroline Vandeleur, Martin Preisig, Roland von Känel, Vladeta Ajdacic-Gross
{"title":"围产期抑郁症的首次发作与特应性疾病以及嗜酸性粒细胞和嗜碱性粒细胞水平持续升高有关。","authors":"En-Young N Wagner, Eva Maria Pichler, Mario Müller, Andrea Eisenhut, Ana Buadze, Yanhua Xu, Erich Seifritz, Marie-Pierre F Strippoli, Enrique Castelao, Setareh Ranjbar, Jennifer Glaus, Caroline Vandeleur, Martin Preisig, Roland von Känel, Vladeta Ajdacic-Gross","doi":"10.1007/s00737-024-01522-5","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>A previous diagnosis of depression is a strong predictor for perinatal depression, apart from other mental disorders, stress, and atopies. It is less clear which factors interfere if perinatal depression occurs as a first depression episode (fePND).</p><p><strong>Methods: </strong>We examined the associations with atopies and related blood parameters using data of CoLaus|PsyCoLaus.</p><p><strong>Results: </strong>Newly occurring depression during the perinatal period but not recurrent depression was associated with a lifetime diagnosis of allergies and asthma together with persistently increased levels of basophils and eosinophils.</p><p><strong>Conclusion: </strong>The results imply that immune function may play a relevant role in the risk of a fePND. If confirmed and detailed, these findings could serve as the basis for designing preliminary prevention strategies by observing eosinophil and basophil levels as well as symptoms of atopic diseases before/during pregnancy.</p>","PeriodicalId":8369,"journal":{"name":"Archives of Women's Mental Health","volume":" ","pages":""},"PeriodicalIF":3.2000,"publicationDate":"2024-10-16","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"First episode depression during the perinatal period is associated with atopic diseases and persistently increased eosinophil and basophil levels.\",\"authors\":\"En-Young N Wagner, Eva Maria Pichler, Mario Müller, Andrea Eisenhut, Ana Buadze, Yanhua Xu, Erich Seifritz, Marie-Pierre F Strippoli, Enrique Castelao, Setareh Ranjbar, Jennifer Glaus, Caroline Vandeleur, Martin Preisig, Roland von Känel, Vladeta Ajdacic-Gross\",\"doi\":\"10.1007/s00737-024-01522-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>A previous diagnosis of depression is a strong predictor for perinatal depression, apart from other mental disorders, stress, and atopies. It is less clear which factors interfere if perinatal depression occurs as a first depression episode (fePND).</p><p><strong>Methods: </strong>We examined the associations with atopies and related blood parameters using data of CoLaus|PsyCoLaus.</p><p><strong>Results: </strong>Newly occurring depression during the perinatal period but not recurrent depression was associated with a lifetime diagnosis of allergies and asthma together with persistently increased levels of basophils and eosinophils.</p><p><strong>Conclusion: </strong>The results imply that immune function may play a relevant role in the risk of a fePND. If confirmed and detailed, these findings could serve as the basis for designing preliminary prevention strategies by observing eosinophil and basophil levels as well as symptoms of atopic diseases before/during pregnancy.</p>\",\"PeriodicalId\":8369,\"journal\":{\"name\":\"Archives of Women's Mental Health\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":3.2000,\"publicationDate\":\"2024-10-16\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Archives of Women's Mental Health\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1007/s00737-024-01522-5\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PSYCHIATRY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Archives of Women's Mental Health","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1007/s00737-024-01522-5","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PSYCHIATRY","Score":null,"Total":0}
First episode depression during the perinatal period is associated with atopic diseases and persistently increased eosinophil and basophil levels.
Purpose: A previous diagnosis of depression is a strong predictor for perinatal depression, apart from other mental disorders, stress, and atopies. It is less clear which factors interfere if perinatal depression occurs as a first depression episode (fePND).
Methods: We examined the associations with atopies and related blood parameters using data of CoLaus|PsyCoLaus.
Results: Newly occurring depression during the perinatal period but not recurrent depression was associated with a lifetime diagnosis of allergies and asthma together with persistently increased levels of basophils and eosinophils.
Conclusion: The results imply that immune function may play a relevant role in the risk of a fePND. If confirmed and detailed, these findings could serve as the basis for designing preliminary prevention strategies by observing eosinophil and basophil levels as well as symptoms of atopic diseases before/during pregnancy.
期刊介绍：
Archives of Women’s Mental Health is the official journal of the International Association for Women''s Mental Health, Marcé Society and the North American Society for Psychosocial Obstetrics and Gynecology (NASPOG). The exchange of knowledge between psychiatrists and obstetrician-gynecologists is one of the major aims of the journal. Its international scope includes psychodynamics, social and biological aspects of all psychiatric and psychosomatic disorders in women. The editors especially welcome interdisciplinary studies, focussing on the interface between psychiatry, psychosomatics, obstetrics and gynecology. Archives of Women’s Mental Health publishes rigorously reviewed research papers, short communications, case reports, review articles, invited editorials, historical perspectives, book reviews, letters to the editor, as well as conference abstracts. Only contributions written in English will be accepted. The journal assists clinicians, teachers and researchers to incorporate knowledge of all aspects of women’s mental health into current and future clinical care and research.
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