2018-2023 年加拿大侵袭性 A 群链球菌高病毒性 M1UK 克隆

IF 7.2 2区医学 Q1 IMMUNOLOGY

Emerging Infectious Diseases Pub Date : 2024-10-20 DOI:10.3201/eid3011.241068

Alyssa R. Golden, Averil Griffith, Gregory J. Tyrrell, Julianne V. Kus, Allison McGeer, Marc-Christian Domingo, Jennifer Grant, Jessica Minion, Paul Van Caeseele, Guillaume Desnoyers, David Haldane, Yang Yu, Xiaofeng Ding, Laura Steven, Jan McFadzen, Courtney Primeau, Irene Martin

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引用次数: 0

摘要

为了确定加拿大的侵袭性 A 群链球菌趋势，我们对 2018-2023 年期间收集的 emm1 分离物进行了特征描述。高病毒性 M1UK 系分离株的比例显著增加，从 2018 年的 22.1%增至 2023 年的 60.2%。基因组分析确定了与毒力噬菌体获得相关的地理和时间上相关的集群和基因。

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Invasive Group A Streptococcus Hypervirulent M1UK Clone, Canada, 2018–2023

To determine invasive group A Streptococcus trends in Canada, we characterized emm1 isolates collected during 2018–2023. The percentage of hypervirulent M1_UK lineage isolates increased significantly, from 22.1% in 2018 to 60.2% in 2023. Genomic analysis identified geographically and temporally associated clusters and genes associated with virulent bacteriophage acquisition.

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来源期刊

Emerging Infectious Diseases 医学-传染病学

CiteScore

17.30

自引率

1.70%

发文量

505

审稿时长

1 months

期刊介绍： Emerging Infectious Diseases is a monthly open access journal published by the Centers for Disease Control and Prevention. The primary goal of this peer-reviewed journal is to advance the global recognition of both new and reemerging infectious diseases, while also enhancing our understanding of the underlying factors that contribute to disease emergence, prevention, and elimination. Targeted towards professionals in the field of infectious diseases and related sciences, the journal encourages diverse contributions from experts in academic research, industry, clinical practice, public health, as well as specialists in economics, social sciences, and other relevant disciplines. By fostering a collaborative approach, Emerging Infectious Diseases aims to facilitate interdisciplinary dialogue and address the multifaceted challenges posed by infectious diseases.