尽早降低胆固醇，并坚持下去！

IF 41.7 1区医学 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS

Nature Reviews Cardiology Pub Date : 2024-10-18 DOI:10.1038/s41569-024-01095-x

Filip K. Swirski, Christoph J. Binder

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引用次数: 0

摘要

摄入高脂肪饮食会导致动脉粥样硬化病变逐渐加重。两项新的研究表明，尽管一生中摄入高脂肪饮食的总体情况相似，但与持续摄入高脂肪饮食相比，生命早期间歇性摄入高脂肪饮食会加速动脉粥样硬化。加速动脉粥样硬化的机制包括巨噬细胞和中性粒细胞的重编程。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Lower your cholesterol early, and stick with it!

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Lower your cholesterol early, and stick with it!

Consumption of a high-fat diet leads to the progressive growth of atherosclerotic lesions. Two new studies document that, despite similar overall exposure to high-fat diet over a lifetime, an intermittent consumption of high-fat diet early in life accelerates atherosclerosis compared with continuous consumption of a high-fat diet. The mechanisms for accelerated atherosclerosis include reprogramming of macrophages and neutrophils.

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来源期刊

Nature Reviews Cardiology 医学-心血管系统

CiteScore

53.10

自引率

0.60%

发文量

143

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Cardiology aims to be the go-to source for reviews and commentaries in the scientific and clinical communities it serves. Focused on providing authoritative and accessible articles enriched with clear figures and tables, the journal strives to offer unparalleled service to authors, referees, and readers, maximizing the usefulness and impact of each publication. It covers a broad range of content types, including Research Highlights, Comments, News & Views, Reviews, Consensus Statements, and Perspectives, catering to practising cardiologists and cardiovascular research scientists. Authored by renowned clinicians, academics, and researchers, the content targets readers in the biological and medical sciences, ensuring accessibility across various disciplines. In-depth Reviews offer up-to-date information, while Consensus Statements provide evidence-based recommendations. Perspectives and News & Views present topical discussions and opinions, and the Research Highlights section filters primary research from cardiovascular and general medical journals. As part of the Nature Reviews portfolio, Nature Reviews Cardiology maintains high standards and a wide reach.