通过下一代测序确定新型 HLA-B*58:139 等位基因的特征

IF 5.9 4区医学 Q2 CELL BIOLOGY

HLA Pub Date : 2024-10-17 DOI:10.1111/tan.15721

Qi Li, Nanying Chen, Lina Dong, Wei Zhang, Faming Zhu

引用次数: 0

摘要

HLA-B*58:139 与 HLA-B*58:01:01:01 等位基因的区别在于外显子 4 中的一个核苷酸替换。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Characterisation of the Novel HLA-B*58:139 Allele by Next-Generation Sequencing

HLA-B*58:139 differs from the HLA-B*58:01:01:01 allele by one nucleotide substitution in exon 4.

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来源期刊

HLA Immunology and Microbiology-Immunology

CiteScore

3.00

自引率

28.80%

发文量

368

期刊介绍： HLA, the journal, publishes articles on various aspects of immunogenetics. These include the immunogenetics of cell surface antigens, the ontogeny and phylogeny of the immune system, the immunogenetics of cell interactions, the functional aspects of cell surface molecules and their natural ligands, and the role of tissue antigens in immune reactions. Additionally, the journal covers experimental and clinical transplantation, the relationships between normal tissue antigens and tumor-associated antigens, the genetic control of immune response and disease susceptibility, and the biochemistry and molecular biology of alloantigens and leukocyte differentiation. Manuscripts on molecules expressed on lymphoid cells, myeloid cells, platelets, and non-lineage-restricted antigens are welcomed. Lastly, the journal focuses on the immunogenetics of histocompatibility antigens in both humans and experimental animals, including their tissue distribution, regulation, and expression in normal and malignant cells, as well as the use of antigens as markers for disease.