来自软珊瑚 Heteroxenia sp.

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2024-10-15 DOI:10.1016/j.tetlet.2024.155323

引用次数: 0

摘要

通过光谱分析、X 射线晶体学以及实验和计算 ECD 研究的比较，确定了 1 和 2 的平面结构和立体化学性质。此外，还进行了抗病毒和抗利什曼原虫试验。化合物 2 对大利什曼原虫具有活性。

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Two isoledene-type sesquiterpenoids from a soft coral Heteroxenia sp.

Two new isoledene-type sesquiterpenoids, 1 and 2, were isolated from an Okinawan soft coral Heteroxenia sp. The planar structures and stereochemistry of 1 and 2 were determined by spectroscopic analysis, X-ray crystallography, and comparison of experimental and calculated ECD studies. Antiviral and anti-leishmania assays were performed. Compound 2 exhibited activity against promastigotes of Leishmania major.

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.