Raupya Suvarna Sutashekhara(一种辅助口服阿育吠陀药的矿物金属制剂)对恶性脑肿瘤患者长期生存的影响

IF 1.7 Q3 INTEGRATIVE & COMPLEMENTARY MEDICINE
Sadanand Sardeshmukh, Vineeta Deshmukh, Arvind Kulkarni, Swapna Kulkarni, Vasanti Godse, Shrinivas Datar, Sushama Bhuvad, Shweta Gujar, Sameer Gore, Bhagyashree Sardeshmukh, Vinita Awalkanthe, Anita Shingte, Sneha Dalvi, Vijay Radye, Sandeep Chavan
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引用次数: 0

摘要

背景脑肿瘤的发病率构成了重大威胁,尤其是生长迅速的高级别肿瘤,尽管采用了各种治疗方法,但仍会严重影响患者的生活质量。阿育吠陀是一种天然药物系统,它通过各种草药、矿物或矿物-矿物-金属配方作为辅助疗法与传统疗法相结合,有助于提高健康效益。其中一种配方是 Raupya Suvarna Sutshekhara(RSS),含有 Raupya bhasma 和 Suvarna bhasma(分别为焚烧银和金)成分,被称为 Rasayana(免疫调节),具有 Medhya(增强大脑功能和智力)活性。材料和方法这项回顾性队列研究的对象是在本中心登记的恶性脑肿瘤患者(n = 110),他们接受了 Raupya Suvarna Sutshekhara 125 毫克-250 毫克(一种草本矿物质金属制剂)的治疗,作为神经滋补剂的首选治疗方法,同时服用辅助的阿育吠陀药物。治疗反应评估期为 3 个月至 5 年(中位数为 29 周)。结果RSS对记忆力减退、头痛、失衡、食欲不振和全身乏力等相关症状有非常显著的疗效(p <0.001),而对尿失禁、癫痫发作、思维/发音困难和身体某一部分/一侧乏力有显著的疗效(p <0.05)。然而,症状混乱/精神错乱的变化并不明显。视力变化、面部麻木或刺痛、吞咽困难和四肢刺痛等症状没有明显改善。体重和 KPS 也有改善。结论 据观察,RSS 的辅助阿育吠陀疗法有助于减轻因肿瘤本身或常规治疗的副作用而引起的症状的严重程度,保持恶性脑肿瘤患者的生活质量,并在治疗期间提高了生存率。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effects of Raupya Suvarna Sutashekhara, a herbo-mineral-metallic formulation as adjunct Oral Ayurvedic Medicine on long-term survival in patients of malignant brain tumor

Background

The incidence of brain tumors poses a significant threat, particularly with high-grade tumors that exhibit rapid growth and can significantly impair the patient's quality of life, despite treatment modalities. Ayurveda, a natural system of medicines helps to enhance health benefits when used as a complementary therapy in combination with conventional treatment through various herbal, herbo-mineral or herbo-mineral-metallic formulations. One of such formulations, Raupya Suvarna Sutshekhara (RSS), has Raupya bhasma and Suvarna bhasma (incinerated Silver and Gold respectively) ingredients and they are described as Rasayana (immunomodulatory) and possess Medhya (enhances the brain functions and intelligence) activity.

Objective

The study documents effects of Raupya Suvarna Sutshekhara in alleviating symptoms of malignant brain tumors.

Materials and methods

This retrospective cohort study was done for malignant brain tumor patients (n = 110) registered at our centre who were treated with Raupya Suvarna Sutshekhara 125 mg–250 mg (a herbo-mineral metallic formulation) as a treatment of choice of neural tonic along with supporting Ayurvedic medicines. Treatment response evaluation period ranged from 3 months to 5 years (median period 29 weeks). Clinical symptoms, weight, Karnofsky Performance Score (KPS), Quality of Life (QoL) score, and survival data with respect to treatment with RSS were analyzed.

Results

RSS showed a very significant (p < 0.001) effect on symptoms related to memory loss, headache, imbalance, loss of appetite, and generalized weakness while significant (p < 0.05) decrease in urinary incontinence, seizures, difficulty in thinking/articulating, and weakness in one part/side of the body. However, a not-quite significant change was seen in symptom confusion/disorientation. No significant improvement was seen in vision changes, facial numbness or tingling, swallowing difficulties, and tingling in extremities. Body weight and KPS also showed improvement. Patients with treatment between 2 and 5 years showed median survival up to 62 months.

Conclusions

It was observed that adjunct Ayurvedic treatment with RSS helped to reduce the severity of symptoms due to the tumor itself or side-effects of conventional treatments, maintain the quality of life of malignant brain tumor patients and has shown to increase survival with respect to the duration of the treatment.
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来源期刊
Journal of Ayurveda and Integrative Medicine
Journal of Ayurveda and Integrative Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-
CiteScore
4.70
自引率
12.50%
发文量
136
审稿时长
30 weeks
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