Yi-Lin Zhang, Tao-Tao Tang, Bin Wang, Yi Wen, Ye Feng, Qing Yin, Wei Jiang, Yue Zhang, Zuo-Lin Li, Min Wu, Qiu-Li Wu, Jing Song, Steven D. Crowley, Hui-Yao Lan, Lin-Li Lv, Bi-Cheng Liu
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引用次数: 0
摘要
空间转录组学》的封面描绘了中国道家的一个概念:阳气通过动态平衡促进组织修复,而阴气失衡则会破坏组织的再生能力,导致纤维化。在编号为 2309752 的文章中,张毅林、吕林丽、刘必成及其合作者利用整合空间单细胞数据绘制了 AKI 向 CKD 转化过程中巨噬细胞的时空异质性图,并发现了一个与纤维化高度相关的新亚群。
Identification of a Novel ECM Remodeling Macrophage Subset in AKI to CKD Transition by Integrative Spatial and Single-Cell Analysis (Adv. Sci. 38/2024)
Spatial Transcriptomic
The cover depicts a Chinese Taoist concept: Yang promotes tissue repair through dynamic equilibrium, while imbalance of Yin disrupts tissue's ability to regenerate, leading to fibrosis. In article number 2309752, Yi-Lin Zhang, Lin-Li Lv, Bi-Cheng Liu, and their co-workers map the spatiotemporal heterogeneity of macrophages in AKI-to-CKD transition using integration spatial single-cell data and identified a novel subset that highly linked to fibrogenesis.
期刊介绍:
Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.