Ruibo Chen, Tianran Cheng, Sisi Xie, Xiaoting Sun, Mingjia Chen, Shumin Zhao, Qingyan Ruan, Xiaolei Ni, Mei Rao, Xinyi Quan, Kaiwen Chen, Shiyue Zhang, Tao Cheng, Yuanfu Xu, Yuguo Chen, Yunlong Yang, Yihai Cao
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引用次数: 0
摘要
激活生热脂肪组织抗白血病在文章编号2402332中,曹义海、杨云龙、陈玉国、徐元富及其同事报道了通过冷暴露或β3-肾上腺素能受体激动剂激活生热脂肪组织(TATs)可明显缓解急性髓性白血病和急性淋巴细胞白血病的发展和恶化。封面描绘了一支身穿棕色衣服的 TAT 部队(棕色脂肪细胞)在冰天雪地中攻击白血病细胞。这项研究表明,以癌症以外的组织为靶点可能是一种抗白血病疗法。美术:徐志超。
Effective Prevention and Treatment of Acute Leukemias in Mice by Activation of Thermogenic Adipose Tissues (Adv. Sci. 38/2024)
Anti-Leukemia by Activation of Thermogenic Adipose Tissues
In article number 2402332, Yihai Cao, Yunlong Yang, Yuguo Chen, Yuanfu Xu, and colleagues report that activating thermogenic adipose tissues (TATs) by cold exposure or β3-adrenergic receptor agonists markedly alleviated development and progression of acute myeloid leukemia and acute lymphoblastic leukemia. The cover portrays a TAT troop clothed in brown (brown adipocytes) assailing a leukemia cell in an icy and snowy milieu. This study indicate that targeting tissues outside of cancer could be an antileukemia therapy. Art by Zhichao Xu.
期刊介绍:
Advanced Science is a prestigious open access journal that focuses on interdisciplinary research in materials science, physics, chemistry, medical and life sciences, and engineering. The journal aims to promote cutting-edge research by employing a rigorous and impartial review process. It is committed to presenting research articles with the highest quality production standards, ensuring maximum accessibility of top scientific findings. With its vibrant and innovative publication platform, Advanced Science seeks to revolutionize the dissemination and organization of scientific knowledge.