使用智能手机和 Photometrix Pro® 软件以数字比色法对四环素药物进行无损分析

IF 0.7 Q4 CHEMISTRY, MULTIDISCIPLINARY

Moscow University Chemistry Bulletin Pub Date : 2024-10-16 DOI:10.3103/S0027131424700354

V. G. Amelin, G. M. Beschastnova, Z. A. Ch. Shogah, A. V. Tretyakov, L. K. Kish

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引用次数: 0

摘要

本研究提出了一种利用智能手机和 3D 打印机打印的设备，通过自身荧光对药物中的四环素进行无损分析的方法。使用化学计量学方法可以缩短分析时间，并将获得的数据可视化。使用 PhotoMetrix PRO® 软件对数据集进行了主成分分析 (PCA)、分层聚类分析 (HCA)、偏最小二乘法 (PLS) 回归和最小二乘法处理。考虑使用化学计量分析方法来确定活性物质的浓度和识别医药产品的制造商。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Non-Destructive Analysis of Tetracycline Drugs by the Digital Colormetric Method Using a Smartphone and the Photometrix Pro® Software

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Non-Destructive Analysis of Tetracycline Drugs by the Digital Colormetric Method Using a Smartphone and the Photometrix Pro® Software

A nondestructive analysis of tetracyclines in drugs by their own fluorescence using a smartphone and a device printed on a 3D printer is proposed. The possibility of using chemometric methods, which reduce the analysis time and visualize the obtained data, is shown. The dataset is processed by principal component analysis (PCA), hierarchical cluster analysis (HCA), partial least squares (PLS) regression, and least squares using the PhotoMetrix PRO^® software. The use of chemometric methods of analysis to determine the concentration of the active substance and identify the manufacturer of medicinal products is considered.

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来源期刊

Moscow University Chemistry Bulletin CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

1.30

自引率

14.30%

发文量

期刊介绍： Moscow University Chemistry Bulletin is a journal that publishes review articles, original research articles, and short communications on various areas of basic and applied research in chemistry, including medical chemistry and pharmacology.