洗必泰和二氧化氯对受变异链球菌生物膜污染的自锁托架抗菌效果的比较评估--体外研究

Q1 Medicine

Journal of oral biology and craniofacial research Pub Date : 2024-10-16 DOI:10.1016/j.jobcr.2024.10.001

Ashish Kumar Singh , Yash Salkar , Puneet Batra , Garima Arora , Shakila Mahesh

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引用次数: 0

摘要

材料和方法将 162 个金属和陶瓷自锁托架（3M™ SmartClip™ & Clarity SL™）随机分为 3 组和 2 个亚组。按照标准程序在所有托架上涂上变异单胞菌生物膜。培养生物膜后，将其置于漱口水的作用下。通过比较变异单胞菌的存活菌落数进行定量评估。采用 Mann-Whitney U 检验比较实验组和对照组的数据。(结果发现，与未经处理的对照组相比，洗必泰葡萄糖酸盐漱口水和二氧化氯漱口水的抗菌效果具有统计学意义（p = 0.00）。洗必泰葡萄糖酸盐漱口水和二氧化氯漱口水在陶瓷自锁托槽组的比较无统计学意义（p = 0.502），在金属自锁托槽组的比较有统计学意义（p = 0.001）。洗必泰双葡萄糖酸盐对金属托槽组更有效。两种漱口水的抗菌效果相当，陶瓷托槽组接触后存活菌落的数量有所不同。

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A comparative evaluation of the antimicrobial efficacy of Chlorhexidine and Chlorine dioxide on self-ligating brackets contaminated with Streptococcus mutans biofilm- An In vitro study

Objective

To evaluate and compare antimicrobial efficacy of Chlorhexidine and Chlorine dioxide mouthwashes on S.mutans biofilm created on metal and ceramic self-ligating brackets.

Materials and methods

A total of 162 metal and ceramic self-ligating brackets (3M™ SmartClip™ & Clarity SL™) were randomly divided into 3 groups and 2 subgroups. Standard procedures were followed to coat all brackets with S.mutans biofilm. The biofilms were cultivated which were then subjected to the effects of the mouthwashes. Quantitative assessment was carried out by comparing the number of viable colonies of S.mutans. A Mann-Whitney U test was used to compare the data between the experimental and control groups. (p < 0.05).

Result

When compared to untreated controls the antimicrobial efficacy of Chlorhexidine Digluconate and Chlorine Dioxide mouthwashes was found to be statistically significant (p = 0.00). The comparison between Chlorhexidine digluconate and Chlorine dioxide mouthwashes was not statistically significant in Ceramic self-ligating group (p = 0.502) and statistically significant in Metal self-ligating group (p = 0.001)

Conclusion

S mutans colonies on metal and ceramic self-ligating brackets can be reduced effectively by Chlorhexidine digluconate and Chlorine dioxide mouthwashes. Chlorhexidine digluconate more effective for metal bracket group. Both mouthwashes had comparable antimicrobial effectiveness, with the difference in the number of viable colonies following exposure for ceramic bracket groups.

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来源期刊

Journal of oral biology and craniofacial research Medicine-Otorhinolaryngology

CiteScore

4.90

自引率

0.00%

发文量

133

审稿时长

167 days

期刊介绍： Journal of Oral Biology and Craniofacial Research (JOBCR)is the official journal of the Craniofacial Research Foundation (CRF). The journal aims to provide a common platform for both clinical and translational research and to promote interdisciplinary sciences in craniofacial region. JOBCR publishes content that includes diseases, injuries and defects in the head, neck, face, jaws and the hard and soft tissues of the mouth and jaws and face region; diagnosis and medical management of diseases specific to the orofacial tissues and of oral manifestations of systemic diseases; studies on identifying populations at risk of oral disease or in need of specific care, and comparing regional, environmental, social, and access similarities and differences in dental care between populations; diseases of the mouth and related structures like salivary glands, temporomandibular joints, facial muscles and perioral skin; biomedical engineering, tissue engineering and stem cells. The journal publishes reviews, commentaries, peer-reviewed original research articles, short communication, and case reports.