Mehmet Topuz, Yuksel Akinay, Erkan Karatas, Tayfun Cetin
{"title":"镁上的 Ti3C2Tx MXene 功能化羟基磷灰石/海泡石纳米管填充聚(乳酸)涂层:体外和抗菌应用","authors":"Mehmet Topuz, Yuksel Akinay, Erkan Karatas, Tayfun Cetin","doi":"10.1016/j.jma.2024.09.017","DOIUrl":null,"url":null,"abstract":"Magnesium (Mg) stands out in temporary biomaterial applications due to its biocompatibility, biodegradability, and low Young's modulus. However, controlling its corrosion through next-generation polymer-based functional coatings is crucial due to the rapid degradation behavior of Mg. In this study, the function of 2D lamellar Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> (MXene) in Hydroxyapatite (HA) and Halloysite nanotube (HNT) hybrid coatings in biodegradable poly– (lactic acid) (PLA) was investigated. The morphological and structural characterizations of the coatings on Mg were revealed through HRTEM, XPS, SEM-EDX, XRD, FTIR, and contact angle analyses/tests. Electrochemical <em>in vitro</em> corrosion tests (OCP, PDS, and EIS-Nyquist) were conducted for evaluate corrosion resistance under simulated body fluid (SBF) conditions. The bioactivity of the coatings in SBF have been revealed in accordance with the ISO 23,317 standard. Finally, antibacterial disk diffusion tests were conducted to investigate the functional effect of MXene in coatings. It has been determined that the presence of MXene in the coating increased not only surface wettability (131°, 85°, 77°, and 74° for uncoated, pH, PHH, and PHH/MXene coatings, respectively) but also increased corrosion resistance (1857.850, 42.357, 1.593, and 0.085 × 10<sup>–6</sup>, A/cm<sup>2</sup> for uncoated, pH, PHH, and PHH/MXene coatings, respectively). It has been proven that the <em>in vitro</em> bioactivity of PLA-HA coatings is further enhanced by adding HNT and MXene, along with SEM morphologies after SBF. Finally, 2D lamellar MXene-filled coating exhibits antibacterial behavior against both <em>E. coli</em> and <em>S. aureus</em> bacteria.","PeriodicalId":16214,"journal":{"name":"Journal of Magnesium and Alloys","volume":null,"pages":null},"PeriodicalIF":15.8000,"publicationDate":"2024-10-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Ti3C2Tx MXene-functionalized Hydroxyapatite/Halloysite nanotube filled poly– (lactic acid) coatings on magnesium: In vitro and antibacterial applications\",\"authors\":\"Mehmet Topuz, Yuksel Akinay, Erkan Karatas, Tayfun Cetin\",\"doi\":\"10.1016/j.jma.2024.09.017\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Magnesium (Mg) stands out in temporary biomaterial applications due to its biocompatibility, biodegradability, and low Young's modulus. However, controlling its corrosion through next-generation polymer-based functional coatings is crucial due to the rapid degradation behavior of Mg. In this study, the function of 2D lamellar Ti<sub>3</sub>C<sub>2</sub>T<sub>x</sub> (MXene) in Hydroxyapatite (HA) and Halloysite nanotube (HNT) hybrid coatings in biodegradable poly– (lactic acid) (PLA) was investigated. The morphological and structural characterizations of the coatings on Mg were revealed through HRTEM, XPS, SEM-EDX, XRD, FTIR, and contact angle analyses/tests. Electrochemical <em>in vitro</em> corrosion tests (OCP, PDS, and EIS-Nyquist) were conducted for evaluate corrosion resistance under simulated body fluid (SBF) conditions. The bioactivity of the coatings in SBF have been revealed in accordance with the ISO 23,317 standard. Finally, antibacterial disk diffusion tests were conducted to investigate the functional effect of MXene in coatings. It has been determined that the presence of MXene in the coating increased not only surface wettability (131°, 85°, 77°, and 74° for uncoated, pH, PHH, and PHH/MXene coatings, respectively) but also increased corrosion resistance (1857.850, 42.357, 1.593, and 0.085 × 10<sup>–6</sup>, A/cm<sup>2</sup> for uncoated, pH, PHH, and PHH/MXene coatings, respectively). It has been proven that the <em>in vitro</em> bioactivity of PLA-HA coatings is further enhanced by adding HNT and MXene, along with SEM morphologies after SBF. Finally, 2D lamellar MXene-filled coating exhibits antibacterial behavior against both <em>E. coli</em> and <em>S. aureus</em> bacteria.\",\"PeriodicalId\":16214,\"journal\":{\"name\":\"Journal of Magnesium and Alloys\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":15.8000,\"publicationDate\":\"2024-10-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Magnesium and Alloys\",\"FirstCategoryId\":\"88\",\"ListUrlMain\":\"https://doi.org/10.1016/j.jma.2024.09.017\",\"RegionNum\":1,\"RegionCategory\":\"材料科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"METALLURGY & METALLURGICAL ENGINEERING\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Magnesium and Alloys","FirstCategoryId":"88","ListUrlMain":"https://doi.org/10.1016/j.jma.2024.09.017","RegionNum":1,"RegionCategory":"材料科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"METALLURGY & METALLURGICAL ENGINEERING","Score":null,"Total":0}
Ti3C2Tx MXene-functionalized Hydroxyapatite/Halloysite nanotube filled poly– (lactic acid) coatings on magnesium: In vitro and antibacterial applications
Magnesium (Mg) stands out in temporary biomaterial applications due to its biocompatibility, biodegradability, and low Young's modulus. However, controlling its corrosion through next-generation polymer-based functional coatings is crucial due to the rapid degradation behavior of Mg. In this study, the function of 2D lamellar Ti3C2Tx (MXene) in Hydroxyapatite (HA) and Halloysite nanotube (HNT) hybrid coatings in biodegradable poly– (lactic acid) (PLA) was investigated. The morphological and structural characterizations of the coatings on Mg were revealed through HRTEM, XPS, SEM-EDX, XRD, FTIR, and contact angle analyses/tests. Electrochemical in vitro corrosion tests (OCP, PDS, and EIS-Nyquist) were conducted for evaluate corrosion resistance under simulated body fluid (SBF) conditions. The bioactivity of the coatings in SBF have been revealed in accordance with the ISO 23,317 standard. Finally, antibacterial disk diffusion tests were conducted to investigate the functional effect of MXene in coatings. It has been determined that the presence of MXene in the coating increased not only surface wettability (131°, 85°, 77°, and 74° for uncoated, pH, PHH, and PHH/MXene coatings, respectively) but also increased corrosion resistance (1857.850, 42.357, 1.593, and 0.085 × 10–6, A/cm2 for uncoated, pH, PHH, and PHH/MXene coatings, respectively). It has been proven that the in vitro bioactivity of PLA-HA coatings is further enhanced by adding HNT and MXene, along with SEM morphologies after SBF. Finally, 2D lamellar MXene-filled coating exhibits antibacterial behavior against both E. coli and S. aureus bacteria.
期刊介绍:
The Journal of Magnesium and Alloys serves as a global platform for both theoretical and experimental studies in magnesium science and engineering. It welcomes submissions investigating various scientific and engineering factors impacting the metallurgy, processing, microstructure, properties, and applications of magnesium and alloys. The journal covers all aspects of magnesium and alloy research, including raw materials, alloy casting, extrusion and deformation, corrosion and surface treatment, joining and machining, simulation and modeling, microstructure evolution and mechanical properties, new alloy development, magnesium-based composites, bio-materials and energy materials, applications, and recycling.