涂抹含酪蛋白磷酸肽-无定形磷酸钙的氟化物清漆和二极管激光照射对白斑病变再矿化的疗效：体外研究

IF 1.8 Q2 DENTISTRY, ORAL SURGERY & MEDICINE

International Orthodontics Pub Date : 2024-10-15 DOI:10.1016/j.ortho.2024.100929

{"title":"涂抹含酪蛋白磷酸肽-无定形磷酸钙的氟化物清漆和二极管激光照射对白斑病变再矿化的疗效：体外研究","authors":"","doi":"10.1016/j.ortho.2024.100929","DOIUrl":null,"url":null,"abstract":"<div><h3>Background/Objectives</h3><div>The prevention of white spot lesions (WSLs) during orthodontic treatment with fixed appliances is of paramount importance to orthodontists. Numerous non-invasive techniques have been extensively researched to effectively manage WSLs. The objective of this study was to investigate the efficacy of MI varnish application, diode laser irradiation and their combination on remineralization of WSLs.</div></div><div><h3>Materials and methods</h3><div>In this in vitro study, 40 enamel samples were divided randomly into 4 groups based on the applied treatment after demineralization. In Group I, MI varnish was applied to the enamel samples for a period of 7 days. In Group II, samples were irradiated with diode laser. In Group III, MI varnish was applied for 7 days, followed by diode laser irradiation. Whereas Group IV (control group) received no treatment and samples were stored in artificial saliva for 7 days. Microhardness assessments were performed at baseline, after demineralization and following the different treatment protocols. A representative sample from each group was randomly selected for scanning electron microscopy (SEM) analysis. One-way ANOVA, repeated measures ANOVA, and Tukey's Post Hoc tests were used for statistical analysis, with significance set at <em>P</em>  <0.05). Group 1 (MI varnish) had a final microhardness mean value of 193.50 (<em>P</em>  =0.018), and Group 3 (MI varnish+diode laser) had a mean of 203.93 (<em>P</em>  ≤0.05.</div></div><div><h3>Results</h3><div>All treatment groups demonstrated significantly higher mean microhardness values compared to the control group (<em>P</em>  <0.001), Group 2 (diode laser) recorded the highest final mean of 214.20 (<em>P</em>    =0.011). SEM observations supported these findings by showing enhanced surface morphology in the treatment groups.</div></div><div><h3>Conclusions</h3><div>MI varnish application, laser irradiation, and their combination demonstrated enhanced microhardness of artificially demineralized enamel, highlighting their effectiveness in remineralization of WSLs.</div></div>\",\"PeriodicalId\":45449,\"journal\":{\"name\":\"International Orthodontics\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2024-10-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"International Orthodontics\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1761722724000858\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"DENTISTRY, ORAL SURGERY & MEDICINE\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"International Orthodontics","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1761722724000858","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"DENTISTRY, ORAL SURGERY & MEDICINE","Score":null,"Total":0}

引用次数: 0

摘要

背景/目的在使用固定矫治器进行正畸治疗期间，预防白斑病（WSL）对正畸医生来说至关重要。为了有效控制白斑病，人们对许多非侵入性技术进行了广泛研究。本研究的目的是探讨涂抹 MI 光油、二极管激光照射以及它们的组合对 WSL 再矿化的效果。第一组，在珐琅质样本上涂抹 MI 光油，为期 7 天。第二组，用二极管激光照射样品。在第三组中，釉质脱矿清漆涂抹 7 天，然后用二极管激光照射。而第四组（对照组）没有进行任何处理，样品在人工唾液中保存 7 天。微硬度评估分别在基线、去矿化后和不同治疗方案后进行。每组随机抽取一个代表性样本进行扫描电子显微镜（SEM）分析。统计分析采用单因素方差分析、重复测量方差分析和 Tukey's 事后检验，显著性设定为 P ≤ 0.05。结果与对照组相比，所有处理组的平均显微硬度值都明显更高（P <0.05）。第 1 组（MI 光油）的最终显微硬度平均值为 193.50 (P < 0.001)，第 2 组（二极管激光）的最终平均值最高，为 214.20 (P = 0.018)，第 3 组（MI 光油 + 二极管激光）的平均值为 203.93 (P = 0.011)。结论MI清漆的使用、激光照射以及它们的组合都提高了人工脱矿化珐琅质的微硬度，突出了它们在WSL再矿化中的有效性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

Efficacy of fluoride varnish containing casein phosphopeptide-amorphous calcium phosphate application and diode laser irradiation on white spot lesions remineralization: An in vitro study

Background/Objectives

The prevention of white spot lesions (WSLs) during orthodontic treatment with fixed appliances is of paramount importance to orthodontists. Numerous non-invasive techniques have been extensively researched to effectively manage WSLs. The objective of this study was to investigate the efficacy of MI varnish application, diode laser irradiation and their combination on remineralization of WSLs.

Materials and methods

In this in vitro study, 40 enamel samples were divided randomly into 4 groups based on the applied treatment after demineralization. In Group I, MI varnish was applied to the enamel samples for a period of 7 days. In Group II, samples were irradiated with diode laser. In Group III, MI varnish was applied for 7 days, followed by diode laser irradiation. Whereas Group IV (control group) received no treatment and samples were stored in artificial saliva for 7 days. Microhardness assessments were performed at baseline, after demineralization and following the different treatment protocols. A representative sample from each group was randomly selected for scanning electron microscopy (SEM) analysis. One-way ANOVA, repeated measures ANOVA, and Tukey's Post Hoc tests were used for statistical analysis, with significance set at P ≤ 0.05.

Results

All treatment groups demonstrated significantly higher mean microhardness values compared to the control group (P < 0.05). Group 1 (MI varnish) had a final microhardness mean value of 193.50 (P < 0.001), Group 2 (diode laser) recorded the highest final mean of 214.20 (P = 0.018), and Group 3 (MI varnish + diode laser) had a mean of 203.93 (P = 0.011). SEM observations supported these findings by showing enhanced surface morphology in the treatment groups.

Conclusions

MI varnish application, laser irradiation, and their combination demonstrated enhanced microhardness of artificially demineralized enamel, highlighting their effectiveness in remineralization of WSLs.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

International Orthodontics DENTISTRY, ORAL SURGERY & MEDICINE-

CiteScore

2.50

自引率

13.30%

发文量

审稿时长

26 days

期刊介绍： Une revue de référence dans le domaine de orthodontie et des disciplines frontières Your reference in dentofacial orthopedics International Orthodontics adresse aux orthodontistes, aux dentistes, aux stomatologistes, aux chirurgiens maxillo-faciaux et aux plasticiens de la face, ainsi quà leurs assistant(e)s. International Orthodontics is addressed to orthodontists, dentists, stomatologists, maxillofacial surgeons and facial plastic surgeons, as well as their assistants.