布氏酸催化的四唑与丙酮的选择性烷基化反应

IF 1.5 4区化学 Q3 CHEMISTRY, ORGANIC

Tetrahedron Letters Pub Date : 2024-10-15 DOI:10.1016/j.tetlet.2024.155327

引用次数: 0

摘要

在 TfOH 催化下进行四氮唑和丙酮的烷基化反应已被证明是一种具有高度区域选择性控制的高效工艺。该方案的特点是起始材料简单易得，反应机理独特，与各种官能团具有良好的兼容性。

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Brønsted acid-catalyzed selective alkylation of tetrazoles with acetone

The alkylation of tetrazole and acetone under the catalysis of TfOH has been shown to be an efficient process with high levels of regioselective control. This protocol features simple and readily accessible starting materials, unique reaction mechanism, excellent compatibility with diverse functional groups.

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来源期刊

Tetrahedron Letters 化学-有机化学

CiteScore

3.50

自引率

5.60%

发文量

521

审稿时长

28 days

期刊介绍： Tetrahedron Letters provides maximum dissemination of outstanding developments in organic chemistry. The journal is published weekly and covers developments in techniques, structures, methods and conclusions in experimental and theoretical organic chemistry. Rapid publication of timely and significant research results enables researchers from all over the world to transmit quickly their new contributions to large, international audiences.