温和条件下聚磷酸与硝酸钾催化钝化芳香族化合物的 C-H 二硝化反应

IF 2.5 3区化学 Q2 CHEMISTRY, ORGANIC

European Journal of Organic Chemistry Pub Date : 2024-10-14 DOI:10.1002/ejoc.202401022

Yixiong Jia, bin Wen, peiran Nan, huaiyin Chen, Xingquan Chen, Shiyun Li

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引用次数: 0

摘要

二硝基芳香族化合物是一种宝贵的有机化合物。然而，这些化合物的高价值也伴随着巨大的风险和艰巨的挑战。在此，我们报告了一种以 KNO3 为硝化剂、聚磷酸为溶剂和催化剂，安全高效地对各种芳香族化合物进行二硝化的方法。这种方法为传统的混合酸体系提供了更安全、更高效的替代方案，使其适用于一系列底物，尤其是高度失活的烯烃。

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Polyphosphoric Acid Catalyzed C-H Dinitration of Passivated Aromatic Compounds with Potassium Nitrate under Mild Condition

Dinitroaromatics are valuable organic compounds. However, the high value of these compounds is accompanied by significant risks and formidable challenges. Herein, we report a safe and highly efficient method for the dinitration of various aromatic compounds, using KNO3 as nitrating agent, polyphosphoric acid as solvent and catalyst. This approach provides a safer and more efficient alternative to the traditional mixed acid system, making it suitable for a range of substrates, especially highly deactivated arenes.

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来源期刊

European Journal of Organic Chemistry 化学-有机化学

CiteScore

5.40

自引率

3.60%

发文量

752

审稿时长

1 months

期刊介绍： The European Journal of Organic Chemistry (2019 ISI Impact Factor 2.889) publishes Full Papers, Communications, and Minireviews from the entire spectrum of synthetic organic, bioorganic and physical-organic chemistry. It is published on behalf of Chemistry Europe, an association of 16 European chemical societies. The following journals have been merged to form two leading journals, the European Journal of Organic Chemistry and the European Journal of Inorganic Chemistry: Liebigs Annalen Bulletin des Sociétés Chimiques Belges Bulletin de la Société Chimique de France Gazzetta Chimica Italiana Recueil des Travaux Chimiques des Pays-Bas Anales de Química Chimika Chronika Revista Portuguesa de Química ACH—Models in Chemistry Polish Journal of Chemistry.