微调蛋白质饥饿感：取决于性别和交配的设定点控制

IF 28.1 1区生物学 Q1 CELL BIOLOGY

Cell Research Pub Date : 2024-10-14 DOI:10.1038/s41422-024-01039-7

Yangkyun Oh, Won-Jae Lee

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引用次数: 0

摘要

虽然碳水化合物、脂肪和蛋白质等宏量营养素的均衡摄入对新陈代谢平衡至关重要，但动物在怀孕等关键生命阶段需要摄入更多蛋白质。吴（Wu）等人最近在《细胞》（Cell）杂志上发表的一篇论文提出了一个新概念，即利用调控果蝇（Drosophila melanogaster）蛋白质食欲控制神经元的两种相反的G蛋白偶联受体（GPCR）信号通路，根据性别和交配状况调整蛋白质摄入设定点。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Fine-tuning protein hunger: sex- and mating-dependent setpoint control

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Fine-tuning protein hunger: sex- and mating-dependent setpoint control

While a balanced intake of macronutrients — carbohydrates, fats, and proteins — is essential for metabolic homeostasis, animals need higher protein intake during critical life stages like pregnancy. A recent paper in Cell by Wu et al. introduces the novel concept of adjusting protein intake setpoints based on sex and mating status, using two opposing G protein-coupled receptor (GPCR) signaling pathways that regulate protein appetite-controlling neurons in the fruit fly, Drosophila melanogaster.

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来源期刊

Cell Research 生物-细胞生物学

CiteScore

53.90

自引率

0.70%

发文量

2420

审稿时长

2.3 months

期刊介绍： Cell Research (CR) is an international journal published by Springer Nature in partnership with the Center for Excellence in Molecular Cell Science, Chinese Academy of Sciences (CAS). It focuses on publishing original research articles and reviews in various areas of life sciences, particularly those related to molecular and cell biology. The journal covers a broad range of topics including cell growth, differentiation, and apoptosis; signal transduction; stem cell biology and development; chromatin, epigenetics, and transcription; RNA biology; structural and molecular biology; cancer biology and metabolism; immunity and molecular pathogenesis; molecular and cellular neuroscience; plant molecular and cell biology; and omics, system biology, and synthetic biology. CR is recognized as China's best international journal in life sciences and is part of Springer Nature's prestigious family of Molecular Cell Biology journals.