E. Gaye , A. Jannin , C. Do Cao , E. Dansin
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{"title":"大细胞神经内分泌癌(LCNEC):2024 年新闻","authors":"E. Gaye , A. Jannin , C. Do Cao , E. Dansin","doi":"10.1016/S1877-1203(24)00095-8","DOIUrl":null,"url":null,"abstract":"<div><div>Large cell neuroendocrine carcinomas (LCNECs) are rare tumors with high grade malignancy and poor prognosis. The management of LCNECs remains complex and several clinical situations (induction, metastatic stages, etc.) are still debating. While the impact of molecular profiling of these tumors on optimal systemic treatment choice has yet to be demonstrated, the prospective evaluation of immunotherapy in metastatic stages is ongoing and could open up new therapeutic options.</div><div>1877-1203/© 2024 SPLF. Published by Elsevier Masson SAS. All rights reserved.</div></div>","PeriodicalId":53645,"journal":{"name":"Revue des Maladies Respiratoires Actualites","volume":"16 2","pages":"Pages 2S250-2S254"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Carcinomes neuroendocrines à grandes cellules (CNEGC) : actualités 2024\",\"authors\":\"E. Gaye , A. Jannin , C. Do Cao , E. Dansin\",\"doi\":\"10.1016/S1877-1203(24)00095-8\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Large cell neuroendocrine carcinomas (LCNECs) are rare tumors with high grade malignancy and poor prognosis. The management of LCNECs remains complex and several clinical situations (induction, metastatic stages, etc.) are still debating. While the impact of molecular profiling of these tumors on optimal systemic treatment choice has yet to be demonstrated, the prospective evaluation of immunotherapy in metastatic stages is ongoing and could open up new therapeutic options.</div><div>1877-1203/© 2024 SPLF. Published by Elsevier Masson SAS. All rights reserved.</div></div>\",\"PeriodicalId\":53645,\"journal\":{\"name\":\"Revue des Maladies Respiratoires Actualites\",\"volume\":\"16 2\",\"pages\":\"Pages 2S250-2S254\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revue des Maladies Respiratoires Actualites\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1877120324000958\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revue des Maladies Respiratoires Actualites","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1877120324000958","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
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