根据世界卫生组织处方指标分析印度尼西亚初级保健中心的用药模式

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH

Clinical Epidemiology and Global Health Pub Date : 2024-10-05 DOI:10.1016/j.cegh.2024.101815

Elida Zairina , Inge Dhamanti , Ida Nurhaida , Davina S. Mutia , Arivazhagan Natesan

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引用次数: 0

摘要

背景医疗保健服务的质量必须适当，以便有效地检测和管理疾病。本研究旨在根据世界卫生组织的处方指标，对印度尼西亚东爪哇省泗水市部分初级医疗保健中心的用药模式进行调查。从患者病历中收集的所有处方均由各基层医疗中心的门诊药房配发。采用世界卫生组织的处方指标对数据进行回顾性分析，以衡量药物使用模式。数据使用 SPSS 27.0 版进行输入、清理和分析。抗生素和注射剂的处方分别占 15.7% 和 1.67%。处方最多的抗生素是阿莫西林（87%）、氯霉素（6.5%）和联合三唑（3%）。根据通用名和基本药物目录处方的药物比例分别为 99.6% 和 76.8%。抗生素处方与患者年龄和处方药物数量有明显关系。19 岁以下患者使用抗生素的几率是其他患者的 2.50 倍（COR：2.50；95 % CI：1.42-4.40）。抗生素处方每增加一个单位，处方药物数量就会增加 0.38 个单位（COR：0.38；95 % CI：0.24-0.59）。抗生素使用次数、注射剂使用次数以及根据基本药物目录开具处方的药物比例均低于世界卫生组织的标准。研究发现，含有通用名的处方比例几乎达到了世卫组织的指标。为促进合理用药，最大限度地减少药物不良反应，有必要对开药行为进行规范和监督。

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Analysing of drug patterns in primary healthcare centers in Indonesia based on WHO's prescribing indicators

Background

The quality of healthcare service delivery must be appropriate to detect and manage disease effectively. Nonetheless, there is a lack of data on the quality of prescribing patterns and healthcare in primary healthcare centers.

Objective

This study aimed to investigate drug use patterns based on the WHO's prescribing indicators among selected primary healthcare centers in Surabaya, East Java, Indonesia.

Methods

This study was cross-sectional descriptive. All prescriptions collected from patient medical records were dispensed from the outpatient pharmacy of each primary healthcare center. Data were retrospectively analyzed using WHO's prescribing indicators to measure drug use patterns. Data were entered, cleaned, and analyzed using SPSS Version 27.0.

Results

About 2.21 drugs were used on average per encounter. Antibiotics and injections were prescribed in 15.7 % and 1.67 % of the encounters. The most prescribed antibiotics were amoxicillin (87 %), chloramphenicol (6.5 %), and co-trimoxazole (3 %). The percentages of drugs prescribed based on the generic name and the essential drug list were 99.6 % and 76.8 %, respectively. Antibiotic prescribing was significantly associated with patient age and the number of medications prescribed. Patients under 19 were 2.50 times more likely to be given antibiotics (COR: 2.50; 95 % CI: 1.42–4.40). Antibiotic prescribing increases by 0.38 units for each unit, increasing the number of medications prescribed (COR: 0.38; 95 % CI: 0.24–0.59).

Conclusion

This study concludes that the prescribing indicators at the five primary healthcare centers in Surabaya, Indonesia differed from the WHO's standards. The antibiotic encounters, injection encounters, and the proportion of drugs prescribed based on the essential drug list were less than the WHO's standards. The study found that the percentage of prescriptions containing generic names was almost fulfilling WHO's indicators. Regulations and monitoring of medicine-prescribing practices are needed to promote rational drug use and minimize adverse drug reactions.

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来源期刊

Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-

CiteScore

4.60

自引率

7.70%

发文量

218

审稿时长

66 days

期刊介绍： Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.