职业铅暴露对气体切割工人综合健康状况的影响

IF 2.3 Q2 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
{"title":"职业铅暴露对气体切割工人综合健康状况的影响","authors":"","doi":"10.1016/j.cegh.2024.101820","DOIUrl":null,"url":null,"abstract":"<div><h3>Background</h3><div>Occupational exposure to hazardous substances, particularly in involving metal cutting and welding industries, poses critical public health concern. This study assesses the health status of gas cutter workers, focusing on Pb exposure.</div></div><div><h3>Method</h3><div>In this cross-sectional study, 40 participants with BLL ≥ 20 μg/dL were recruited from workers engaged in oxy-acetylene metal cutting. These workers were compared to an age-, sex-, and sociodemographic-matched control group (n=42) from the same workplace. Health assessments including routine clinical and laboratory investigations along with BLL, and markers of calcium homeostasis were carried out.</div></div><div><h3>Results</h3><div>Gas cutters exhibited significantly higher mean systolic BP and elevated SGOT levels, with similar prevalence of respiratory symptoms and musculoskeletal disorders in both groups. No significant differences were found in most hematological, liver, and renal parameters. However, gas cutters had significantly higher PTH levels and lower serum vitamin D levels. Pulmonary function tests indicated significantly reduced FVC, FEV1, FEV1/FVC ratio, FEF25-75%, and PEFR in gas cutters, as well as markedly higher CRP levels.</div></div><div><h3>Conclusion</h3><div>Gas cutters experience significant health impacts compared to controls, including elevated systolic BP, impaired pulmonary function, and disturbance in calcium homeostasis due to occupational Pb exposure. Higher CRP levels suggest notable inflammatory responses. These findings highlight the urgent need for targeted interventions and regular monitoring to mitigate health risks associated with Pb exposure among gas cutter workers.</div></div>","PeriodicalId":46404,"journal":{"name":"Clinical Epidemiology and Global Health","volume":null,"pages":null},"PeriodicalIF":2.3000,"publicationDate":"2024-10-11","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Impact of Occupational Lead Exposure on the Comprehensive Health Status of Gas Cutter Workers\",\"authors\":\"\",\"doi\":\"10.1016/j.cegh.2024.101820\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Background</h3><div>Occupational exposure to hazardous substances, particularly in involving metal cutting and welding industries, poses critical public health concern. This study assesses the health status of gas cutter workers, focusing on Pb exposure.</div></div><div><h3>Method</h3><div>In this cross-sectional study, 40 participants with BLL ≥ 20 μg/dL were recruited from workers engaged in oxy-acetylene metal cutting. These workers were compared to an age-, sex-, and sociodemographic-matched control group (n=42) from the same workplace. Health assessments including routine clinical and laboratory investigations along with BLL, and markers of calcium homeostasis were carried out.</div></div><div><h3>Results</h3><div>Gas cutters exhibited significantly higher mean systolic BP and elevated SGOT levels, with similar prevalence of respiratory symptoms and musculoskeletal disorders in both groups. No significant differences were found in most hematological, liver, and renal parameters. However, gas cutters had significantly higher PTH levels and lower serum vitamin D levels. Pulmonary function tests indicated significantly reduced FVC, FEV1, FEV1/FVC ratio, FEF25-75%, and PEFR in gas cutters, as well as markedly higher CRP levels.</div></div><div><h3>Conclusion</h3><div>Gas cutters experience significant health impacts compared to controls, including elevated systolic BP, impaired pulmonary function, and disturbance in calcium homeostasis due to occupational Pb exposure. Higher CRP levels suggest notable inflammatory responses. These findings highlight the urgent need for targeted interventions and regular monitoring to mitigate health risks associated with Pb exposure among gas cutter workers.</div></div>\",\"PeriodicalId\":46404,\"journal\":{\"name\":\"Clinical Epidemiology and Global Health\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":2.3000,\"publicationDate\":\"2024-10-11\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Epidemiology and Global Health\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2213398424003178\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Epidemiology and Global Health","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2213398424003178","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH","Score":null,"Total":0}
引用次数: 0

摘要

背景职业暴露于有害物质,特别是涉及金属切割和焊接行业的有害物质,是公众健康的重大问题。本研究评估了气割工人的健康状况,重点关注铅暴露。方法在这项横断面研究中,从从事氧-乙炔金属切割的工人中招募了 40 名 BLL≥20 μg/dL 的参与者。这些工人与来自同一工作场所、年龄、性别和社会人口学匹配的对照组(42 人)进行了比较。结果气割工人的平均收缩压明显升高,SGOT水平升高,两组工人的呼吸道症状和肌肉骨骼疾病发生率相似。大多数血液学、肝脏和肾脏参数没有发现明显差异。不过,气割工的 PTH 水平明显较高,血清维生素 D 水平较低。肺功能测试显示,气割工的 FVC、FEV1、FEV1/FVC 比值、FEF25-75% 和 PEFR 明显降低,CRP 水平明显升高。较高的 CRP 水平表明存在明显的炎症反应。这些研究结果突出表明,迫切需要采取有针对性的干预措施并进行定期监测,以降低气割工人与铅暴露相关的健康风险。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Impact of Occupational Lead Exposure on the Comprehensive Health Status of Gas Cutter Workers

Background

Occupational exposure to hazardous substances, particularly in involving metal cutting and welding industries, poses critical public health concern. This study assesses the health status of gas cutter workers, focusing on Pb exposure.

Method

In this cross-sectional study, 40 participants with BLL ≥ 20 μg/dL were recruited from workers engaged in oxy-acetylene metal cutting. These workers were compared to an age-, sex-, and sociodemographic-matched control group (n=42) from the same workplace. Health assessments including routine clinical and laboratory investigations along with BLL, and markers of calcium homeostasis were carried out.

Results

Gas cutters exhibited significantly higher mean systolic BP and elevated SGOT levels, with similar prevalence of respiratory symptoms and musculoskeletal disorders in both groups. No significant differences were found in most hematological, liver, and renal parameters. However, gas cutters had significantly higher PTH levels and lower serum vitamin D levels. Pulmonary function tests indicated significantly reduced FVC, FEV1, FEV1/FVC ratio, FEF25-75%, and PEFR in gas cutters, as well as markedly higher CRP levels.

Conclusion

Gas cutters experience significant health impacts compared to controls, including elevated systolic BP, impaired pulmonary function, and disturbance in calcium homeostasis due to occupational Pb exposure. Higher CRP levels suggest notable inflammatory responses. These findings highlight the urgent need for targeted interventions and regular monitoring to mitigate health risks associated with Pb exposure among gas cutter workers.
求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Clinical Epidemiology and Global Health
Clinical Epidemiology and Global Health PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
CiteScore
4.60
自引率
7.70%
发文量
218
审稿时长
66 days
期刊介绍: Clinical Epidemiology and Global Health (CEGH) is a multidisciplinary journal and it is published four times (March, June, September, December) a year. The mandate of CEGH is to promote articles on clinical epidemiology with focus on developing countries in the context of global health. We also accept articles from other countries. It publishes original research work across all disciplines of medicine and allied sciences, related to clinical epidemiology and global health. The journal publishes Original articles, Review articles, Evidence Summaries, Letters to the Editor. All articles published in CEGH are peer-reviewed and published online for immediate access and citation.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
确定
请完成安全验证×
copy
已复制链接
快去分享给好友吧!
我知道了
右上角分享
点击右上角分享
0
联系我们:info@booksci.cn Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。 Copyright © 2023 布克学术 All rights reserved.
京ICP备2023020795号-1
ghs 京公网安备 11010802042870号
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术官方微信