{"title":"用于检测药物原料纯度的新型微波微流控传感器","authors":"Fahimeh Jafari, Mazdak Rad Malekshahi","doi":"10.1016/j.aeue.2024.155541","DOIUrl":null,"url":null,"abstract":"<div><div>A novel microwave microfluidic sensor is offered for purity detection of medicine’s raw materials which is composed of two radial components and a PDMS microfluidic holder to apply the test samples. The basis of the sensing method is the shift in the resonance frequency and quality factor of the resonator in the presence of liquids with different complex permittivity. To investigate the performance of the proposed sensor, various solvents, binary mixtures of ethanol–water, and raw materials of 3 different medicines have been checked and a 980 MHz variation of resonance frequency, which provided a very high sensitivity equal to 0.53, was achieved for a complex permittivity range of 1–78.4. The proposed sensor has a small size, simple design, easy fabrication process, and very high sensitivity while it is fabricated on an FR4 substrate which decreases the total cost significantly.</div></div>","PeriodicalId":50844,"journal":{"name":"Aeu-International Journal of Electronics and Communications","volume":"187 ","pages":"Article 155541"},"PeriodicalIF":3.0000,"publicationDate":"2024-09-26","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"A novel microwave microfluidic sensor for purity detection of Medicines’ raw materials\",\"authors\":\"Fahimeh Jafari, Mazdak Rad Malekshahi\",\"doi\":\"10.1016/j.aeue.2024.155541\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>A novel microwave microfluidic sensor is offered for purity detection of medicine’s raw materials which is composed of two radial components and a PDMS microfluidic holder to apply the test samples. The basis of the sensing method is the shift in the resonance frequency and quality factor of the resonator in the presence of liquids with different complex permittivity. To investigate the performance of the proposed sensor, various solvents, binary mixtures of ethanol–water, and raw materials of 3 different medicines have been checked and a 980 MHz variation of resonance frequency, which provided a very high sensitivity equal to 0.53, was achieved for a complex permittivity range of 1–78.4. The proposed sensor has a small size, simple design, easy fabrication process, and very high sensitivity while it is fabricated on an FR4 substrate which decreases the total cost significantly.</div></div>\",\"PeriodicalId\":50844,\"journal\":{\"name\":\"Aeu-International Journal of Electronics and Communications\",\"volume\":\"187 \",\"pages\":\"Article 155541\"},\"PeriodicalIF\":3.0000,\"publicationDate\":\"2024-09-26\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Aeu-International Journal of Electronics and Communications\",\"FirstCategoryId\":\"94\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S1434841124004278\",\"RegionNum\":3,\"RegionCategory\":\"计算机科学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"ENGINEERING, ELECTRICAL & ELECTRONIC\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Aeu-International Journal of Electronics and Communications","FirstCategoryId":"94","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S1434841124004278","RegionNum":3,"RegionCategory":"计算机科学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"ENGINEERING, ELECTRICAL & ELECTRONIC","Score":null,"Total":0}
A novel microwave microfluidic sensor for purity detection of Medicines’ raw materials
A novel microwave microfluidic sensor is offered for purity detection of medicine’s raw materials which is composed of two radial components and a PDMS microfluidic holder to apply the test samples. The basis of the sensing method is the shift in the resonance frequency and quality factor of the resonator in the presence of liquids with different complex permittivity. To investigate the performance of the proposed sensor, various solvents, binary mixtures of ethanol–water, and raw materials of 3 different medicines have been checked and a 980 MHz variation of resonance frequency, which provided a very high sensitivity equal to 0.53, was achieved for a complex permittivity range of 1–78.4. The proposed sensor has a small size, simple design, easy fabrication process, and very high sensitivity while it is fabricated on an FR4 substrate which decreases the total cost significantly.
期刊介绍:
AEÜ is an international scientific journal which publishes both original works and invited tutorials. The journal''s scope covers all aspects of theory and design of circuits, systems and devices for electronics, signal processing, and communication, including:
signal and system theory, digital signal processing
network theory and circuit design
information theory, communication theory and techniques, modulation, source and channel coding
switching theory and techniques, communication protocols
optical communications
microwave theory and techniques, radar, sonar
antennas, wave propagation
AEÜ publishes full papers and letters with very short turn around time but a high standard review process. Review cycles are typically finished within twelve weeks by application of modern electronic communication facilities.