{"title":"围手术期患者急性肾损伤的预防和管理","authors":"Natalie Drury, Andrew Lewington","doi":"10.1016/j.mpsur.2024.07.008","DOIUrl":null,"url":null,"abstract":"<div><div>Acute kidney injury should be regarded as a medical emergency and a biomarker of acute illness. It is detected by rises in serum creatinine or reductions in urine output and is a common and costly surgical complication, increasing length of stay, perioperative morbidity and mortality. Imperative to improving outcomes of patients with AKI is recognition of patients at risk, with the institution of preventative measures and the prompt treatment of those developing AKI. There are new therapies in the pipeline for AKI but in the interim the effectiveness of the application of a simple AKI care bundle should not be underestimated. The STOP AKI approach is centred on promoting better recognition of four key pillars in the management of AKI. These include treatment of Sepsis, stopping and avoiding Toxins, Optimization of blood pressure and fluid status and review Prescribing to include the treatment of complications.</div></div>","PeriodicalId":74889,"journal":{"name":"Surgery (Oxford, Oxfordshire)","volume":"42 10","pages":"Pages 748-752"},"PeriodicalIF":0.0000,"publicationDate":"2024-10-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevention and management of acute kidney injury in the perioperative patient\",\"authors\":\"Natalie Drury, Andrew Lewington\",\"doi\":\"10.1016/j.mpsur.2024.07.008\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><div>Acute kidney injury should be regarded as a medical emergency and a biomarker of acute illness. It is detected by rises in serum creatinine or reductions in urine output and is a common and costly surgical complication, increasing length of stay, perioperative morbidity and mortality. Imperative to improving outcomes of patients with AKI is recognition of patients at risk, with the institution of preventative measures and the prompt treatment of those developing AKI. There are new therapies in the pipeline for AKI but in the interim the effectiveness of the application of a simple AKI care bundle should not be underestimated. The STOP AKI approach is centred on promoting better recognition of four key pillars in the management of AKI. These include treatment of Sepsis, stopping and avoiding Toxins, Optimization of blood pressure and fluid status and review Prescribing to include the treatment of complications.</div></div>\",\"PeriodicalId\":74889,\"journal\":{\"name\":\"Surgery (Oxford, Oxfordshire)\",\"volume\":\"42 10\",\"pages\":\"Pages 748-752\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2024-10-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Surgery (Oxford, Oxfordshire)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0263931924001273\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Surgery (Oxford, Oxfordshire)","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0263931924001273","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 0
摘要
急性肾损伤应被视为医疗急症和急性疾病的生物标志物。急性肾损伤可通过血清肌酐升高或尿量减少检测出来,是一种常见且代价高昂的外科并发症,会增加住院时间、围手术期发病率和死亡率。要改善 AKI 患者的预后,必须识别高危患者,采取预防措施,并对发生 AKI 的患者进行及时治疗。目前正在研究治疗 AKI 的新疗法,但在此期间,不应低估应用简单的 AKI 护理包的效果。STOP AKI 方法的核心是促进更好地认识 AKI 管理的四大支柱。这包括治疗败血症、停止和避免使用毒素、优化血压和体液状态以及审查处方以包括并发症的治疗。
Prevention and management of acute kidney injury in the perioperative patient
Acute kidney injury should be regarded as a medical emergency and a biomarker of acute illness. It is detected by rises in serum creatinine or reductions in urine output and is a common and costly surgical complication, increasing length of stay, perioperative morbidity and mortality. Imperative to improving outcomes of patients with AKI is recognition of patients at risk, with the institution of preventative measures and the prompt treatment of those developing AKI. There are new therapies in the pipeline for AKI but in the interim the effectiveness of the application of a simple AKI care bundle should not be underestimated. The STOP AKI approach is centred on promoting better recognition of four key pillars in the management of AKI. These include treatment of Sepsis, stopping and avoiding Toxins, Optimization of blood pressure and fluid status and review Prescribing to include the treatment of complications.