用 2-氨基苯甲醛和环胺构建融合喹唑啉酮的铜和电催化协同作用†。

IF 3.9 3区化学 Q2 CHEMISTRY, MULTIDISCIPLINARY

RSC Advances Pub Date : 2024-10-11 DOI:10.1039/D4RA06539E

Yujie Shi, Ganpeng Li, Ruirui Wang, Xiao-jing Zhao and Yonghui He

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引用次数: 0

摘要

我们开发了一种新的铜和电催化协同策略，用于高效构建融合喹唑啉酮。在醋酸铜和氧气的存在下，芳基酮和 1,2,3,4- 四氢异喹啉可以顺利地参与这一转化过程，从而在不分裂的单元中提供各种取代的喹唑啉酮。该反应显示出良好的官能团耐受性，并能在温和的条件下以良好的收率提供通用的喹唑啉酮。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Copper and electrocatalytic synergy for the construction of fused quinazolinones with 2-aminobenzaldehydes and cyclic amines†

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Copper and electrocatalytic synergy for the construction of fused quinazolinones with 2-aminobenzaldehydes and cyclic amines†

A new copper and electrocatalytic synergy strategy for efficiently constructing fused quinazolinones has been developed. In the presence of cupric acetate and oxygen, aryl ketones and 1,2,3,4-tetrahydroisoquinoline can smoothly participate in this transformation, thus providing a variety of substituted quinazolones in an undivided cell. The reaction shows good functional group tolerance and provides universal quinazolinones at a good yield under mild conditions.

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来源期刊

RSC Advances chemical sciences-

CiteScore

7.50

自引率

2.60%

发文量

3116

审稿时长

1.6 months

期刊介绍： An international, peer-reviewed journal covering all of the chemical sciences, including multidisciplinary and emerging areas. RSC Advances is a gold open access journal allowing researchers free access to research articles, and offering an affordable open access publishing option for authors around the world.