小儿眼睑皮角：病例系列和文献综述

IF 4.1 1区医学 Q1 OPHTHALMOLOGY

American Journal of Ophthalmology Pub Date : 2024-10-10 DOI:10.1016/j.ajo.2024.09.034

RAMEZ BARBARA , AHMED M. ABDELAAL , REBECCA LEVY , ANITA NAGY , KAMIAR MIRESKANDARI , ASIM ALI

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引用次数: 0

摘要

目的：描述小儿眼睑皮肤角的临床和组织病理学特征：设计：回顾性观察病例系列和文献综述：五名患有眼睑皮角的小儿患者方法：确定五名患有眼睑皮角的小儿患者：利用科室数据库回顾性地确定了五例眼睑皮肤角。分析了患者的人口统计学数据、临床表现、组织学结果和临床病程。对 3 名患者的病变进行了切除活检。其余2名患者接受了保守治疗：临床结果和组织病理学评估，重点是排除恶性肿瘤：5例皮肤角病变均通过手术或保守治疗得到缓解。平均发病年龄为 6.6 岁（5-11 岁）。从临床上看，4 例病变前均有角化瘤或霰粒肿，所有切除的病变在组织学检查中均为良性。未观察到有丝分裂或不典型性。在 1 至 96 个月的随访期间，没有一名患者复发。通过查阅文献，我们发现之前有五篇关于五个病例的报道。我们的病例系列使这一数字翻了一番，证明了这些病变在儿童中的良性性质：结论：小儿眼睑皮肤角与眼睑边缘炎症密切相关，似乎是良性病变。结论：小儿眼睑皮角与眼睑边缘炎症密切相关，而且似乎是良性病变，这与成人的情况形成鲜明对比，因为成人的眼睑皮角常常与肿瘤有关。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Pediatric Eyelid Cutaneous Horns: A Case Series and Literature Review

Purpose

To describe the clinical and histopathologic features of pediatric eyelid cutaneous horns.

Design

Retrospective observational case series and review of literature.

Subjects

Five pediatric patients with eyelid cutaneous horns.

Methods

Five cases with eyelid cutaneous horns were retrospectively identified using departmental databases. Patients’ records were analyzed for demographic data, clinical appearance, histologic findings, and clinical course. An excisional biopsy of the lesion was performed in 3 patients. The remaining 2 patients were managed conservatively.

Main outcome measures

Clinical outcome and histopathologic evaluation with emphasis on excluding malignancy.

Results

All 5 cutaneous horn lesions resolved surgically or conservatively. The average age at presentation was 6.6 years (range 5-11 years). Clinically, 4 lesions were preceded by a hordeolum or chalazion and all excised lesions had benign features on histologic examination. Mitotic figures or atypia were not observed. None of the patients developed recurrence during the follow-up period ranging from 1 to 96 months.

Five previous reports of five cases were found on review of the literature. Our case series doubles this number to support the benign nature of these lesions in children.

Conclusions

Pediatric eyelid cutaneous horns are closely related to eyelid margin inflammatory disease and appear to follow a benign course. This contrasts with the adult population where cutaneous horns are frequently associated with neoplasia.

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来源期刊

American Journal of Ophthalmology 医学-眼科学

CiteScore

9.20

自引率

7.10%

发文量

406

审稿时长

36 days

期刊介绍： The American Journal of Ophthalmology is a peer-reviewed, scientific publication that welcomes the submission of original, previously unpublished manuscripts directed to ophthalmologists and visual science specialists describing clinical investigations, clinical observations, and clinically relevant laboratory investigations. Published monthly since 1884, the full text of the American Journal of Ophthalmology and supplementary material are also presented online at www.AJO.com and on ScienceDirect. The American Journal of Ophthalmology publishes Full-Length Articles, Perspectives, Editorials, Correspondences, Books Reports and Announcements. Brief Reports and Case Reports are no longer published. We recommend submitting Brief Reports and Case Reports to our companion publication, the American Journal of Ophthalmology Case Reports. Manuscripts are accepted with the understanding that they have not been and will not be published elsewhere substantially in any format, and that there are no ethical problems with the content or data collection. Authors may be requested to produce the data upon which the manuscript is based and to answer expeditiously any questions about the manuscript or its authors.