一名复发性肺结核成年患者的双侧慢性腔隙性肺曲霉瘤:病例报告和文献综述。

IF 0.9 Q3 MEDICINE, GENERAL & INTERNAL
Telila Mesfin Tadesse, Oliyad Shegene, Sisay Dadi Abebe, Eshetu Mesfin Tadesse, Biniyam Sahiledengle, Mesfin Tsegaye Jima
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引用次数: 0

摘要

背景:曲霉瘤是烟曲霉菌的球状生长,是肺部的一种良性曲霉菌病。它通常影响免疫力低下和肺部结构有缺陷的患者。尽管有 10% 的病例会自发消退,但大多数曲霉瘤病例都没有症状。大多数患者的病变没有任何症状。曲霉瘤的诊断需要曲霉菌的直接血清学或微生物学证据以及放射学证据:我们描述了一名 35 岁的奥罗莫族成年男性患者,他盗汗、间歇性有痰咳嗽并伴有稀薄的白色痰液、食欲不振、易疲劳已持续 3 个月。5 年前,他曾因肺结核接受过治疗,涂片呈阳性,随后被证明痊愈。客观上,他呼吸急促,肋间、肋下和锁骨上回缩,胸部活动对称。高分辨率计算机断层扫描显示双侧肺尖腔病变,核心软组织衰减球形肿块和空气新月征提示曲霉瘤,痰液光镜检查证实了这一点。患者接受了抗生素和抗真菌药物治疗:曲霉瘤是慢性肺曲霉病的一种症状,慢性肺曲霉病是由曲霉菌持续感染引起的一类肺部疾病。原发性曲霉瘤并不常见,经常发生在免疫系统受损的人群中。长期咳嗽、发烧、胸痛和咯血都是肺曲霉瘤的症状。大多数情况下,肺曲霉菌病很难被发现。尽管死亡率和发病率都很高,但手术仍然是治疗肺曲霉瘤最有效的方法。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Bilateral chronic cavitary pulmonary aspergillomas in an adult patient with recurrent tuberculosis: a case report and literature review.

Background: Aspergillomas are globular growths of Aspergillus fumigatus, a benign aspergillosis of the lungs. It usually affects patients who are immunocompromised and have anatomically defective lung structures. The majority of aspergilloma cases are asymptomatic, despite the fact that 10% of cases spontaneously resolve. Most patients do not have any symptoms from their lesions. Direct serological or microbiological evidence of an Aspergillus species along with radiologic evidence is required for the diagnosis of an aspergilloma.

Case: We describe a 35-year-old adult Oromo male patient who had been experiencing night sweats, an intermittent productive cough with sparse whitish sputum, loss of appetite, and easy fatigability for 3 months. At 5 years prior, he received treatment for pulmonary tuberculosis that was smear-positive and was subsequently certified healed. Objectively, he was tachypneic and had intercostal, subcostal, and supraclavicular retractions with symmetric chest movement. A high-resolution computed tomography scan revealed bilateral apical cavitary lesions with core soft tissue attenuating spherical masses and an air crescentic sign suggestive of aspergillomas, which were confirmed by sputum light microscopic examination. The patient was managed with antibiotics and antifungals.

Conclusion: Aspergilloma is a symptom of chronic pulmonary aspergillosis, a category of lung disorders caused by a persistent Aspergillus infection. Primary aspergillomas are uncommon and frequently occur in people with compromised immune systems. A prolonged cough, fever, chest pain, and hemoptysis are all symptoms of pulmonary aspergillomas. The majority of the time, pulmonary aspergillosis is difficult to identify. Despite high mortality and morbidity rates, surgery is still the most effective treatment for pulmonary aspergilloma.

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来源期刊
Journal of Medical Case Reports
Journal of Medical Case Reports Medicine-Medicine (all)
CiteScore
1.50
自引率
0.00%
发文量
436
期刊介绍: JMCR is an open access, peer-reviewed online journal that will consider any original case report that expands the field of general medical knowledge. Reports should show one of the following: 1. Unreported or unusual side effects or adverse interactions involving medications 2. Unexpected or unusual presentations of a disease 3. New associations or variations in disease processes 4. Presentations, diagnoses and/or management of new and emerging diseases 5. An unexpected association between diseases or symptoms 6. An unexpected event in the course of observing or treating a patient 7. Findings that shed new light on the possible pathogenesis of a disease or an adverse effect
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