Stimuli-responsive actuation enabled by selective host-guest recognition of urea cage

Organic cages, featuring the selective stimuli response and reversible encapsulation of guest molecules, demonstrate a huge potential in guest-triggered actuation. In this issue of Chem, Khashab and co-workers exploited host-guest recognition of organic urea cages with three-dimensional structures to integrate multiple mechanical actuations into a single material for the first time.