转录暂停是萌芽血管生成的分子机制。

IF 9.4 Q1 CARDIAC & CARDIOVASCULAR SYSTEMS
Inês Cebola, Graeme M. Birdsey, Anna M. Randi
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引用次数: 0

摘要

深入的体内和体外功能分析以及一系列基因组测定揭示了 RNF20 是控制血管萌芽生成过程中内皮血管内皮生长因子和 Notch 信号之间平衡的分子调速器。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

Transcriptional pausing as a molecular mechanism of sprouting angiogenesis

Transcriptional pausing as a molecular mechanism of sprouting angiogenesis
In-depth in vivo and in vitro functional analyses, along with a series of genomic assays, reveal RNF20 as a molecular rheostat controlling the balance between endothelial VEGF and Notch signaling during sprouting angiogenesis.
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CiteScore
5.70
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0.00%
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