中重度脑外伤患者坚持进行高频生态瞬间评估。

IF 4.6 Q2 MATERIALS SCIENCE, BIOMATERIALS
Amanda R Rabinowitz, Tessa Hart
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引用次数: 0

摘要

目的:生态瞬间评估(EMA)涉及重复收集实时自我报告数据,通常每天收集多次,几乎总是通过智能手机进行电子传输。虽然 EMA 在研究多种人群的内部状态、行为和经历方面显示出了良好的前景,但其在认知障碍样本(如与慢性中重度创伤性脑损伤(TBI)相关的样本)中的可行性仍令人担忧:本研究考察了中重度 TBI 患者对为期 7 周的高频率(每天 5 次)EMA 方案的依从性,同时考虑了随时间推移的响应率变化以及参与者的个体特征(记忆功能、教育程度、受伤严重程度和年龄):在 39 名参与者的样本中,平均总体应答率为 65%(范围:5%-100%)。线性混合效应模型显示,在 7 周的参与过程中,应答率呈线性下降趋势,下降幅度较小,但具有统计学意义。随机斜率的显著影响表明,个体轨迹是可变的。较高的反应率与较高的教育程度和较好的记忆功能呈正相关(统计趋势),而年龄和受伤严重程度的影响并不明显:这些发现揭示了 EMA 在创伤性脑损伤研究中的潜力,但也强调了有必要采取量身定制的策略来解决个人在坚持治疗方面的障碍。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Adherence to high-frequency ecological momentary assessment in persons with moderate-to-severe traumatic brain injury.

Objective: Ecological momentary assessment (EMA) involves repeated collection of real-time self-report data, often multiple times per day, nearly always delivered electronically by smartphone. While EMA has shown promise for researching internal states, behaviors, and experiences in multiple populations, concerns remain regarding its feasibility in samples with cognitive impairments, like those associated with chronic moderate-to-severe traumatic brain injury (TBI).

Methods: This study examines adherence to a 7-week high-frequency (5x daily) EMA protocol in individuals with moderate-to-severe TBI, considering changes in response rate over time, as well as individual participant characteristics (memory function, education, injury severity, and age).

Results: In the sample of 39 participants, the average overall response rate was 65% (range: 5%-100%). Linear mixed-effects modeling revealed a small but statistically significant linear decay in response rate over 7 weeks of participation. Individual trajectories were variable, as evidenced by the significant effect of random slope. A better response rate was positively associated with greater educational attainment and better episodic memory function (statistical trend), whereas the effects of age and injury severity were not significant.

Conclusions: These findings shed light on the potential of EMA in TBI studies but underscore the need for tailored strategies to address individual barriers to adherence.

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来源期刊
ACS Applied Bio Materials
ACS Applied Bio Materials Chemistry-Chemistry (all)
CiteScore
9.40
自引率
2.10%
发文量
464
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