Kyota Shinfuku, Naoki Takasaka, Ryutaro Ohashi, Taiki Fukuda, Makiko Takatsuka, Ryo Sato, Mitsuyoshi Mita, Tsukasa Hasegawa, Masami Yamada, Yumie Yamanaka, Yusuke Hosaka, Kai Ryu, Tokio Hoshina, Hiroshi Takeda, Takeo Ishikawa, Jun Araya
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引用次数: 0
摘要
我们报告了一例在家庭氧疗（HOT）过程中因鼻中隔穿孔导致感染性心内膜炎（IE）的病例。一名有间质性肺炎（IP）病史并正在接受 HOT 治疗的 64 岁男性因呼吸困难住院。血液培养中反复检测到对甲氧西林敏感的金黄色葡萄球菌（MSSA）。超声心动图显示三尖瓣植被和反流。根据修改后的杜克标准，患者被诊断为 IE。全身检查发现鼻中隔穿孔，并从鼻腔分离出 MSSA。患者接受了头孢唑啉和克林霉素治疗。然而，他出现了吸入性肺炎，随后死亡。MSSA 的进入途径是鼻粘膜受损，这是在 HOT 期间干燥和刮除干燥鼻涕造成的。鼻中隔穿孔是 HOT 的潜在并发症，可能会导致严重的细菌感染。因此，在 HOT 期间勤加护理鼻腔至关重要。
Infective endocarditis due to nasal septal perforation during home oxygen therapy.
We report a case of infective endocarditis (IE) due to nasal septal perforation during Home oxygen therapy (HOT). A 64-year-old man with a history of interstitial pneumonia (IP) and on HOT was hospitalized for dyspnea. Methicillin-sensitive Staphylococcus aureus (MSSA) was repeatedly detected in blood cultures. Echocardiography revealed tricuspid valve vegetation and regurgitation. The patient was diagnosed with IE, according to the modified Duke criteria. A full-body examination revealed nasal septal perforation and MSSA was isolated from the nasal cavity. The patient was treated with cefazolin and clindamycin. However, he developed aspiration pneumonia and subsequently died. The portal of entry of MSSA was damaged nasal mucosa, caused by dryness and curettage of the dried nasal mucus during HOT. Nasal septal perforation, a potential complication of HOT, may cause severe bacterial infections. Consequently, diligent nasal care is crucial during HOT.
期刊介绍：
Respirology Case Reports is an open-access online journal dedicated to the publication of original clinical case reports, case series, clinical images and clinical videos in all fields of respiratory medicine. The Journal encourages the international exchange between clinicians and researchers of experiences in diagnosing and treating uncommon diseases or diseases with unusual presentations. All manuscripts are peer-reviewed through a streamlined process that aims at providing a rapid turnaround time from submission to publication.
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