COVID-19 大流行对德国一家转诊中心泌尿肿瘤疾病治疗效果的影响。

IF 1.5 4区医学 Q3 UROLOGY & NEPHROLOGY

Urologia Internationalis Pub Date : 2024-10-09 DOI:10.1159/000541932

Moustafa Elleisy, Desiree Louise Dräger, Heike Zettl, Oliver W Hakenberg

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引用次数: 0

摘要

简介为了评估Covid-19大流行之前、期间和之后泌尿肿瘤病例转诊和病理结果的差异，比较2018年至2023年在一所大学医疗中心进行的癌症手术的临床和病理数据：我们收集了212名前列腺癌（PCa）根治性前列腺切除术（RP）患者、157名膀胱癌（BCa）根治性膀胱切除术（RC）患者、36名上尿路上皮癌（UTUC）根治性肾切除术（RNU）患者的数据、133名肾癌肾部分切除术（PN）患者和160名根治性肾切除术（RN）患者，93名睾丸癌睾丸切除术患者，39名新诊断阴茎癌患者。将2018年至2020年2月（Covid-19大流行之前）接受治疗的患者数据与2020年3月至2022年3月（Covid-19大流行期间）和2022年4月至2023年2月（Covid-19大流行之后）接受治疗的患者数据进行了比较：在主要病理特征方面，接受 RP、RNU、睾丸切除术或包皮环切术和/或阴茎切除术的患者没有发现差异。此外，在 Covid-19 大流行后诊断出的 RN 肿瘤病理分期较低（p<0.05）。与 Covid-19 大流行前的队列相比，大流行期间阴茎癌的诊断年龄更高（p<0.05），但这并不意味着病理分期或淋巴结受累情况更差。另一个值得注意的变化是睾丸切除术的住院时间（LOS）比大流行前缩短了（p<0.05）：结论：在 Covid-19 大流行之前、期间和之后，我院均未观察到泌尿肿瘤学活动或病理学特征的下降。Covid-19大流行后，RN的病理肿瘤分期明显降低。在Covid-19大流行期间，阴茎癌的确诊年龄明显增加，睾丸切除术的LOS也有所下降。

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COVID-19 Pandemic Impact on Uro-Oncological Disease Outcomes at a German Referral Center.

Introduction: To assess differences in referral and pathologic outcomes for uro-oncology cases prior to, during, and after the COVID-19 pandemic, comparing clinical and pathological data from cancer surgeries performed at a university medical center between 2018 and 2023.

Methods: We collected data of 212 patients with radical prostatectomy (RP) for prostate cancer, 157 patients with radical cystectomies (RCs) for bladder cancer, 36 patients with radical nephroureterectomies (RNUs) for upper tract urothelial carcinoma, 133 patients with partial nephrectomies (PNs), and 160 patients with radical nephrectomies (RNs) for renal cancer, 93 patients with orchifunicolectomy for testicular cancer, 39 patients with newly diagnosed penile cancer. Data from patients treated between 2018 and February 2020 (before the COVID-19 pandemic) were compared with data from patients treated between March 2020 and March 2022 (during the COVID-19 pandemic) and between April 2022 and February 2023 (after the COVID-19 pandemic).

Results: No differences in terms of main pathologic features were observed in patients undergoing RP, RNU, orchifunicolectomy, or circumcision and/or penectomy. Further, a lower pathological tumor stage was diagnosed for RN after the COVID-19 pandemic (p < 0.05). A higher age at diagnosis for penile cancer was observed during the pandemic cohort in comparison to the pre-COVID-19 pandemic cohort (p < 0.05), but this did not translate into a worse pathological stage or lymph node involvement. Another notable change was the shortening of the length of stay (LOS) for orchifunicolectomy over the pandemic (p < 0.05).

Conclusion: Neither decline in uro-oncologic activity nor pathological features were observed at our institution before, during, and after the COVID-19 pandemic. A significantly lower pathological tumor stage for RN after the COVID-19 pandemic was seen. Penile cancer was diagnosed at a significantly higher age during the COVID-19 pandemic, and a decrease in LOS for orchifunicolectomy was observed.

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来源期刊

Urologia Internationalis 医学-泌尿学与肾脏学

CiteScore

3.30

自引率

6.20%

发文量

审稿时长

3-8 weeks

期刊介绍： Concise but fully substantiated international reports of clinically oriented research into science and current management of urogenital disorders form the nucleus of original as well as basic research papers. These are supplemented by up-to-date reviews by international experts on the state-of-the-art of key topics of clinical urological practice. Essential topics receiving regular coverage include the introduction of new techniques and instrumentation as well as the evaluation of new functional tests and diagnostic methods. Special attention is given to advances in surgical techniques and clinical oncology. The regular publication of selected case reports represents the great variation in urological disease and illustrates treatment solutions in singular cases.