Marzieh Najjaran, Siamak Zarei-Ghanavati, Hadi Ostadimoghaddam, Abbasali Yekta, Nasser Shoeibi, Armin Hemmati, Mojtaba Abrishami, Saeed Akhlaghi, Mohammed Ziaei
{"title":"早产儿的眼部生物测量和光学相干断层扫描参数:队列研究","authors":"Marzieh Najjaran, Siamak Zarei-Ghanavati, Hadi Ostadimoghaddam, Abbasali Yekta, Nasser Shoeibi, Armin Hemmati, Mojtaba Abrishami, Saeed Akhlaghi, Mohammed Ziaei","doi":"10.1155/2024/2381582","DOIUrl":null,"url":null,"abstract":"<p><strong>Purpose: </strong>To compare biometric and optical coherence tomography parameters as well as refractive status in preterm children aged 4-8 years with or without retinopathy of prematurity (ROP), and evaluate their correlations with age and gender-matched full-term children.</p><p><strong>Methods: </strong>Retrospective comparative cohort study of four groups of children. Children with a history of preterm birth, including ROP who received intravitreal bevacizumab (IVB) treatment, children with a history of ROP that regressed without treatment and those with no history of ROP were compared to age and gender-matched full-term children as a control group. Best corrected visual acuity (BCVA), spherical equivalent of refraction (SE), macular and choroidal thickness, as well as biometric parameters was measured.</p><p><strong>Results: </strong>A total of 120 eyes of 120 children (30 children in each group) were included. There was no significant difference in BCVA, SE, and subjective cylinder between groups (<i>p</i>=0.05, <i>p</i>=0.3, <i>p</i>=0.6, respectively). Axial length was significantly shorter, and the cornea was steeper in both ROP groups than in other groups (<i>p</i>=0.001, <i>p</i> < 0.001, respectively). The central macular thickness was significantly thicker in the treated, regressed ROP and preterm groups than in full-term children (<i>p</i> < 0.001). The gestational age was negatively correlated with macular thickness in both treated and regressed ROP groups (<i>r</i> = -0.517; <i>p</i>=0.003, <i>r</i> = - 0.490; <i>p</i>=0.006, respectively).</p><p><strong>Conclusions: </strong>Children with a history of ROP had a shorter axial length, steeper cornea, and thicker macula that correlated with lower gestational age.</p>","PeriodicalId":16674,"journal":{"name":"Journal of Ophthalmology","volume":null,"pages":null},"PeriodicalIF":1.8000,"publicationDate":"2024-09-30","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458276/pdf/","citationCount":"0","resultStr":"{\"title\":\"Ocular Biometric and Optical Coherence Tomography Parameters in Former Preterm Children: A Cohort Study.\",\"authors\":\"Marzieh Najjaran, Siamak Zarei-Ghanavati, Hadi Ostadimoghaddam, Abbasali Yekta, Nasser Shoeibi, Armin Hemmati, Mojtaba Abrishami, Saeed Akhlaghi, Mohammed Ziaei\",\"doi\":\"10.1155/2024/2381582\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Purpose: </strong>To compare biometric and optical coherence tomography parameters as well as refractive status in preterm children aged 4-8 years with or without retinopathy of prematurity (ROP), and evaluate their correlations with age and gender-matched full-term children.</p><p><strong>Methods: </strong>Retrospective comparative cohort study of four groups of children. Children with a history of preterm birth, including ROP who received intravitreal bevacizumab (IVB) treatment, children with a history of ROP that regressed without treatment and those with no history of ROP were compared to age and gender-matched full-term children as a control group. Best corrected visual acuity (BCVA), spherical equivalent of refraction (SE), macular and choroidal thickness, as well as biometric parameters was measured.</p><p><strong>Results: </strong>A total of 120 eyes of 120 children (30 children in each group) were included. There was no significant difference in BCVA, SE, and subjective cylinder between groups (<i>p</i>=0.05, <i>p</i>=0.3, <i>p</i>=0.6, respectively). Axial length was significantly shorter, and the cornea was steeper in both ROP groups than in other groups (<i>p</i>=0.001, <i>p</i> < 0.001, respectively). The central macular thickness was significantly thicker in the treated, regressed ROP and preterm groups than in full-term children (<i>p</i> < 0.001). The gestational age was negatively correlated with macular thickness in both treated and regressed ROP groups (<i>r</i> = -0.517; <i>p</i>=0.003, <i>r</i> = - 0.490; <i>p</i>=0.006, respectively).</p><p><strong>Conclusions: </strong>Children with a history of ROP had a shorter axial length, steeper cornea, and thicker macula that correlated with lower gestational age.</p>\",\"PeriodicalId\":16674,\"journal\":{\"name\":\"Journal of Ophthalmology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.8000,\"publicationDate\":\"2024-09-30\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC11458276/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Ophthalmology\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1155/2024/2381582\",\"RegionNum\":4,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"2024/1/1 0:00:00\",\"PubModel\":\"eCollection\",\"JCR\":\"Q3\",\"JCRName\":\"OPHTHALMOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Ophthalmology","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1155/2024/2381582","RegionNum":4,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"2024/1/1 0:00:00","PubModel":"eCollection","JCR":"Q3","JCRName":"OPHTHALMOLOGY","Score":null,"Total":0}
Ocular Biometric and Optical Coherence Tomography Parameters in Former Preterm Children: A Cohort Study.
Purpose: To compare biometric and optical coherence tomography parameters as well as refractive status in preterm children aged 4-8 years with or without retinopathy of prematurity (ROP), and evaluate their correlations with age and gender-matched full-term children.
Methods: Retrospective comparative cohort study of four groups of children. Children with a history of preterm birth, including ROP who received intravitreal bevacizumab (IVB) treatment, children with a history of ROP that regressed without treatment and those with no history of ROP were compared to age and gender-matched full-term children as a control group. Best corrected visual acuity (BCVA), spherical equivalent of refraction (SE), macular and choroidal thickness, as well as biometric parameters was measured.
Results: A total of 120 eyes of 120 children (30 children in each group) were included. There was no significant difference in BCVA, SE, and subjective cylinder between groups (p=0.05, p=0.3, p=0.6, respectively). Axial length was significantly shorter, and the cornea was steeper in both ROP groups than in other groups (p=0.001, p < 0.001, respectively). The central macular thickness was significantly thicker in the treated, regressed ROP and preterm groups than in full-term children (p < 0.001). The gestational age was negatively correlated with macular thickness in both treated and regressed ROP groups (r = -0.517; p=0.003, r = - 0.490; p=0.006, respectively).
Conclusions: Children with a history of ROP had a shorter axial length, steeper cornea, and thicker macula that correlated with lower gestational age.
期刊介绍:
Journal of Ophthalmology is a peer-reviewed, Open Access journal that publishes original research articles, review articles, and clinical studies related to the anatomy, physiology and diseases of the eye. Submissions should focus on new diagnostic and surgical techniques, instrument and therapy updates, as well as clinical trials and research findings.