The Effects of Numerical Evidence and Message Framing in Communicating Vaccine Efficacy.

To examine the effects of numerical evidence and message framing in communicating vaccine efficacy information about infectious diseases, an online experiment presented to U.S. adults different versions of a vaccination promotional message that vary by numerical vaccine efficacy evidence: (low efficacy rate: 60% vs. high efficacy rate: 95%), outcome framing (preventing disease-related infection vs. preventing disease-related severe illness), and gain vs. loss framing, using a factorial between-subjects design. While there was no significant interaction between numerical vaccine efficacy evidence and message framing, findings showed that a higher vaccine efficacy rate increased positive beliefs about vaccination and outcome framing emphasizing infection prevention increased message processing fluency. Given that infectious diseases pose higher risks for severe illness among older adults, follow-up analyses by age showed that only younger adults were sensitive to message framing where outcome framing emphasizing infection prevention increased processing fluency.