从菌群失调到平衡：油酸在阴道中的作用

IF 20.6 1区医学 Q1 MICROBIOLOGY

Cell host & microbe Pub Date : 2024-10-09 DOI:10.1016/j.chom.2024.09.007

Ri-hua Xie, Hao Liu, Cancan Qi, Yan He

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引用次数: 0

摘要

脂肪酸在塑造阴道微生物群方面的作用仍不清楚。在一期《细胞》杂志上，Zhu 等人利用基因组和转录组分析揭示了油酸（OA）能选择性地抑制 L. iners，同时促进 L. crispatus，为治疗细菌性阴道病（BV）提出了新策略。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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From dysbiosis to homeostasis: Oleic acid matters in the vagina

The role of fatty acids in shaping vaginal microbiota remains unclear. In an issue of Cell, Zhu et al. use genomic and transcriptomic analyses to reveal that oleic acid (OA) selectively inhibits L. iners while promoting L. crispatus, suggesting new strategies for the treatment of bacterial vaginosis (BV).

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来源期刊

Cell host & microbe 生物-微生物学

CiteScore

45.10

自引率

1.70%

发文量

201

审稿时长

4-8 weeks

期刊介绍： Cell Host & Microbe is a scientific journal that was launched in March 2007. The journal aims to provide a platform for scientists to exchange ideas and concepts related to the study of microbes and their interaction with host organisms at a molecular, cellular, and immune level. It publishes novel findings on a wide range of microorganisms including bacteria, fungi, parasites, and viruses. The journal focuses on the interface between the microbe and its host, whether the host is a vertebrate, invertebrate, or plant, and whether the microbe is pathogenic, non-pathogenic, or commensal. The integrated study of microbes and their interactions with each other, their host, and the cellular environment they inhabit is a unifying theme of the journal. The published work in Cell Host & Microbe is expected to be of exceptional significance within its field and also of interest to researchers in other areas. In addition to primary research articles, the journal features expert analysis, commentary, and reviews on current topics of interest in the field.