发现癌基因诱导的衰老

IF 81.3 1区生物学 Q1 CELL BIOLOGY

Nature Reviews Molecular Cell Biology Pub Date : 2024-10-09 DOI:10.1038/s41580-024-00791-3

Akiko Takahashi

引用次数: 0

摘要

Akiko Takahashi 讨论了塞拉诺等人在 1997 年发表的开创性论文，他们发现癌基因激活会导致与复制衰老相似的表型，从而确立了衰老与癌症之间的联系。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

The discovery of oncogene-induced senescence

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The discovery of oncogene-induced senescence

Akiko Takahashi discusses the seminal 1997 paper by Serrano et al. who found that oncogene activation results in a similar phenotype to replicative senescence, establishing the connection between senescence and cancer.

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来源期刊

Nature Reviews Molecular Cell Biology 生物-细胞生物学

CiteScore

173.60

自引率

0.50%

发文量

118

审稿时长

6-12 weeks

期刊介绍： Nature Reviews Molecular Cell Biology is a prestigious journal that aims to be the primary source of reviews and commentaries for the scientific communities it serves. The journal strives to publish articles that are authoritative, accessible, and enriched with easily understandable figures, tables, and other display items. The goal is to provide an unparalleled service to authors, referees, and readers, and the journal works diligently to maximize the usefulness and impact of each article. Nature Reviews Molecular Cell Biology publishes a variety of article types, including Reviews, Perspectives, Comments, and Research Highlights, all of which are relevant to molecular and cell biologists. The journal's broad scope ensures that the articles it publishes reach the widest possible audience.