迷走神经背运动核发出的信号促进空肠脂肪吸收

IF 3.7 3区医学 Q2 CHEMISTRY, MEDICINAL

Chemical Research in Toxicology Pub Date : 2024-10-08 DOI:10.1038/s41574-024-01048-x

Senegal Carty

引用次数: 0

摘要

迷走神经背运动核（DMV）的传出神经与胃肠系统相连，被认为可以调节消化。目前正在积极研究迷走神经控制营养吸收的机制。发表在《自然》（Nature）上的一项研究表明，DMV神经元的一个亚群通过调节空肠微绒毛的长度来控制肠道对食物脂肪的吸收。这种方法发现，异黄酮类葛根素抑制了DMV的活动。"论文作者柳倩倩、薛文智、张春雷和王继秋说："此外，我们还利用光亲和性标记来识别与葛根素结合的蛋白质。研究结果表明，葛根素可能以抑制性受体GABAA的一个亚基GABRA1为靶标。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Signals from the dorsal motor nucleus of the vagus promote jejunal fat absorption

查看原文本刊更多论文

Signals from the dorsal motor nucleus of the vagus promote jejunal fat absorption

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Chemical Research in Toxicology 医学-毒理学

CiteScore

7.90

自引率

7.30%

发文量

215

审稿时长

3.5 months

期刊介绍： Chemical Research in Toxicology publishes Articles, Rapid Reports, Chemical Profiles, Reviews, Perspectives, Letters to the Editor, and ToxWatch on a wide range of topics in Toxicology that inform a chemical and molecular understanding and capacity to predict biological outcomes on the basis of structures and processes. The overarching goal of activities reported in the Journal are to provide knowledge and innovative approaches needed to promote intelligent solutions for human safety and ecosystem preservation. The journal emphasizes insight concerning mechanisms of toxicity over phenomenological observations. It upholds rigorous chemical, physical and mathematical standards for characterization and application of modern techniques.