一家三级甲等医院通过甲状腺功能检测评估的甲状腺功能障碍患者:一项回顾性研究。

IF 0.9 Q4 PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH
Pan African Medical Journal Pub Date : 2024-09-04 eCollection Date: 2024-01-01 DOI:10.11604/pamj.2024.49.7.44173
Emmanuel Donkoh Aidoo, Grace Korkor Ababio, Benjamin Arko-Boham, Emmanuel Ayitey Tagoe, Nii Ayite Aryee
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引用次数: 0

摘要

导言:以往针对非洲人群的研究并未利用甲状腺激素谱广泛描述甲状腺功能障碍的范围。虽然缺碘是非洲常见的甲状腺疾病,但它并不代表患者甲状腺功能障碍的全部范围。这项回顾性研究旨在描述加纳阿克拉的一家三级甲等医院--科勒-布教学医院(Korle-Bu Teaching Hospital,KBTH)就诊的甲状腺功能障碍患者的甲状腺功能障碍谱。方法:对2019年1月至2021年12月期间KBTH内科就诊的所有甲状腺疾病的医疗记录进行了回顾性分析。提取了患者人口统计学信息和甲状腺激素谱(三碘甲状腺原氨酸-FT3、甲状腺素-FT4和促甲状腺激素-TSH)信息,并进行了描述性统计。结果:在215名甲状腺疾病患者中,女性占85.1%(n=183),男性占14.9%(n=32)。患者的平均年龄为 45±14 岁,大多数患者的年龄在 31-50 岁之间(49.3%;n=106)。报告最多的甲状腺功能障碍是原发性甲状腺功能亢进(57.7%),其次分别是原发性甲状腺功能减退(22.3%)、亚临床甲状腺功能亢进(9.3%)、甲状腺功能亢进综合征(6.5%)和亚临床甲状腺功能减退(4.6%)。结论:原发性甲状腺功能亢进症是最常见的甲状腺功能障碍。甲状腺功能亢进症与心脏疾病的发病率和死亡率有关。需要及时采取干预措施,以降低甲状腺功能亢进症的发病风险和负担。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Thyroid dysfunction among patients assessed by thyroid function tests at a tertiary care hospital: a retrospective study.

Introduction: previous studies in African populations have not extensively described the spectrum of thyroid dysfunction using the profile of thyroid hormones. Although iodine deficiency is a common thyroid disorder in Africa, it does not represent the entire spectrum of thyroid dysfunction seen in patients. This retrospective study aimed to describe the spectrum of thyroid dysfunction among patients seen at the Korle-Bu Teaching Hospital (KBTH), a tertiary care hospital in Accra, Ghana.

Methods: a retrospective analysis of medical records of all consultations on thyroid disorders seen at the Internal Medicine Department of KBTH between January 2019 and December 2021 was conducted. Information on patient demographics, and thyroid hormone profiles (triiodothyronine - FT3, thyroxine - FT4, and thyroid stimulating hormone - TSH) were extracted and subjected to descriptive statistics. The thyroid hormone profiles of the subjects were analyzed and classified into thyroid dysfunction categories using guidelines from the American Thyroid Association (ATA).

Results: out of the 215 patients with thyroid disorders enrolled, 85.1% (n=183) were females and 14.9% (n=32), were males. The mean age of patients was 45±14 years, with most of the patients within the age range of 31-50 years (49.3%; n=106). The most reported thyroid function dysfunction was primary hyperthyroidism (57.7%), followed by primary hypothyroidism (22.3%), subclinical hyperthyroidism (9.3%), euthyroid sick syndrome (6.5%), and subclinical hypothyroidism (4.6%) respectively.

Conclusion: primary hyperthyroidism was the most commonly diagnosed thyroid dysfunction. Hyperthyroidism has been associated with cardiac morbidity and mortality. Timely interventions are required to reduce the morbidity risks and burden associated with the hyperthyroid state.

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来源期刊
Pan African Medical Journal
Pan African Medical Journal PUBLIC, ENVIRONMENTAL & OCCUPATIONAL HEALTH-
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